Acute or chronic irreversible respiratory failure may occur in patients undergoing pneumonectomy. Aim of this study was to determine transcriptome expression changes after experimental pneumonectomy in swine model. Experimental left pneumonectomy was performed in five pigs under general anaesthesia. Both the resected and the remaining lung, after 60 post-operative completely uneventful days, underwent genome-wide bulk RNA-Sequencing (RNA-Seq).
Genome-wide expression of the residual lung reacting to experimental Pneumonectomy / Napolioni, Valerio; Bianconi, Fortunato; Potenza, Rossella; Carpi, Francesco M; Ludovini, Vienna; Picciolini, Matteo; Tofanetti, Francesca R; Bufalari, Antonello; Pallotti, Stefano; Poggi, Camilla; Anile, Marco; Daddi, Niccolò; Venuta, Federico; Puma, Francesco; Vannucci, Jacopo. - In: BMC GENOMICS. - ISSN 1471-2164. - 22:(2021). [10.1186/s12864-021-08171-3]
Genome-wide expression of the residual lung reacting to experimental Pneumonectomy
Potenza, Rossella;Poggi, Camilla;Anile, Marco;Venuta, Federico;Vannucci, Jacopo
2021
Abstract
Acute or chronic irreversible respiratory failure may occur in patients undergoing pneumonectomy. Aim of this study was to determine transcriptome expression changes after experimental pneumonectomy in swine model. Experimental left pneumonectomy was performed in five pigs under general anaesthesia. Both the resected and the remaining lung, after 60 post-operative completely uneventful days, underwent genome-wide bulk RNA-Sequencing (RNA-Seq).| File | Dimensione | Formato | |
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