Common precursors for liver, biliary tree and pancreas exist at an early stage of development in the definitive endoderm forming the foregut. We have identified and characterized endodermal stem/progenitor cells with regenerative potential persisting in the adult human duodenum.
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential / Cardinale, Vincenzo; Carpino, Guido; Overi, Diletta; Safarikia, Samira; Zhang, Wencheng; Kanke, Matt; Franchitto, Antonio; Costantini, Daniele; Riccioni, Olga; Nevi, Lorenzo; Chiappetta, Michele; Onori, Paolo; Franchitto, Matteo; Bini, Simone; Hung, Yu-Han; Lai, Quirino; Zizzari, Ilaria; Nuti, Marianna; Nicoletti, Carmine; Checquolo, Saula; Di Magno, Laura; Giuli, Maria Valeria; Rossi, Massimo; Sethupathy, Praveen; Reid, Lola M; Alvaro, Domenico; Gaudio, Eugenio. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - (2022). [10.1016/j.jhep.2022.08.037]
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential
Cardinale, Vincenzo;Carpino, Guido;Overi, Diletta;Safarikia, Samira;Franchitto, Antonio;Costantini, Daniele;Riccioni, Olga;Nevi, Lorenzo;Chiappetta, Michele;Onori, Paolo;Franchitto, Matteo;Bini, Simone;Lai, Quirino;Zizzari, Ilaria;Nuti, Marianna;Nicoletti, Carmine;Checquolo, Saula;Di Magno, Laura;Giuli, Maria Valeria;Rossi, Massimo;Alvaro, Domenico;Gaudio, Eugenio
2022
Abstract
Common precursors for liver, biliary tree and pancreas exist at an early stage of development in the definitive endoderm forming the foregut. We have identified and characterized endodermal stem/progenitor cells with regenerative potential persisting in the adult human duodenum.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
