Introduction: The aim of this study was to evaluate the effects of a low-dose exposure to nickel, as it is present in urban air, on thyroid hormones and on thyrotropin in outdoor workers exposed to urban pollutants. Materials and Methods: A total of 164 outdoor workers were studied and divided by sex and smoking habit. Each worker underwent measurement of urinary nickel and of blood triiodothyronine, L-thyroxine, and thyrotropin levels. The statistical analysis was performed. Results: Statistical analysis shows a significant and positive correlation between urinary nickel and L-thyroxine, both in total sample and in males. Discussion and Conclusion: The study suggests that occupational exposure to a low dose of nickel may affect thyroid function in municipal police workers. These data may provide information on other categories of outdoor workers with similar exposure.

Low-Dose Occupational Exposure to Nickel and Thyroid Hormones

Grazia Giammichele;Vittorio Antuono;Beatrice Loreti;Francesco Tomei;Roberto Massimi;Stefania Marchione;Anastasia Suppi;Gianfranco Tomei;Serafino Ricci
2022

Abstract

Introduction: The aim of this study was to evaluate the effects of a low-dose exposure to nickel, as it is present in urban air, on thyroid hormones and on thyrotropin in outdoor workers exposed to urban pollutants. Materials and Methods: A total of 164 outdoor workers were studied and divided by sex and smoking habit. Each worker underwent measurement of urinary nickel and of blood triiodothyronine, L-thyroxine, and thyrotropin levels. The statistical analysis was performed. Results: Statistical analysis shows a significant and positive correlation between urinary nickel and L-thyroxine, both in total sample and in males. Discussion and Conclusion: The study suggests that occupational exposure to a low dose of nickel may affect thyroid function in municipal police workers. These data may provide information on other categories of outdoor workers with similar exposure.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1658187
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