Purpose of Review: Myocardial left ventricular (LV) hypertrophy (LVH) is a common phenotype associated to increased morbidity and mortality. Beyond an accurate LV mass quantification, cardiovascular magnetic resonance (CMR) can also provide tissue characterization, perfusion, and deformation assessments. Aim of the present review is to discuss recent advances in CMR imaging of LVH. Recent Findings: T1 and T2 mapping techniques expanded the ability of CMR in phenotyping LVH, underscoring the pathogenic significance of interstitial fibrosis and edema in hypertrophic conditions. Perfusion and deformation assessments revealed dysfunctional correlates not uncommonly associated to LVH. Late gadolinium enhancement (LGE) highlighted the role of replacement fibrosis as a marker of advanced disease. Finally, the prognostic relevance of both interstitial and replacement fibrosis has been demonstrated in several LVH conditions. Summary: CMR is an efficient tool for differential diagnosis of LVH phenotypes. Furthermore, it can often provide prognostic information, potentially guiding treatment and improving clinical management.

CMR in hypertrophic cardiac conditions—an update / Kolentinis, M.; Maestrini, V.; Vidalakis, E.; Cimino, S.; Arcari, L.. - In: CURRENT CARDIOVASCULAR IMAGING REPORTS. - ISSN 1941-9066. - 13:4(2020). [10.1007/s12410-020-9533-1]

CMR in hypertrophic cardiac conditions—an update

Maestrini V.
Secondo
;
Cimino S.;Arcari L.
Ultimo
2020

Abstract

Purpose of Review: Myocardial left ventricular (LV) hypertrophy (LVH) is a common phenotype associated to increased morbidity and mortality. Beyond an accurate LV mass quantification, cardiovascular magnetic resonance (CMR) can also provide tissue characterization, perfusion, and deformation assessments. Aim of the present review is to discuss recent advances in CMR imaging of LVH. Recent Findings: T1 and T2 mapping techniques expanded the ability of CMR in phenotyping LVH, underscoring the pathogenic significance of interstitial fibrosis and edema in hypertrophic conditions. Perfusion and deformation assessments revealed dysfunctional correlates not uncommonly associated to LVH. Late gadolinium enhancement (LGE) highlighted the role of replacement fibrosis as a marker of advanced disease. Finally, the prognostic relevance of both interstitial and replacement fibrosis has been demonstrated in several LVH conditions. Summary: CMR is an efficient tool for differential diagnosis of LVH phenotypes. Furthermore, it can often provide prognostic information, potentially guiding treatment and improving clinical management.
2020
cardiovascular magnetic resonance imaging; fibrosis; late gadolinium enhancement; left ventricular hypertrophy; prognosis; t1 and t2 mapping
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
CMR in hypertrophic cardiac conditions—an update / Kolentinis, M.; Maestrini, V.; Vidalakis, E.; Cimino, S.; Arcari, L.. - In: CURRENT CARDIOVASCULAR IMAGING REPORTS. - ISSN 1941-9066. - 13:4(2020). [10.1007/s12410-020-9533-1]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1657556
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