The kinetics of electron entry in beef heart cytochrome c oxidase have been studied by stopped-flow spectroscopy following chemical modification of the CuA site with mercurials. In this derivative CuA is no longer reducible by cytochrome c while cytochrome alpha may accept electrons from the latter with rates comparable to the native enzyme. The results indicate that CuA is not the exclusive electron entry site in cytochrome c oxidase.
The kinetics of electron entry in cytochrome c oxidase / Malatesta, F.; Antonin, G.; Sarti, P.; Vallone, B.; Brunori, M.. - In: BIOLOGY OF METALS. - ISSN 0933-5854. - 3:2(1990), pp. 118-121. [10.1007/BF01179517]
The kinetics of electron entry in cytochrome c oxidase
Sarti, P.;Vallone, B.;
1990
Abstract
The kinetics of electron entry in beef heart cytochrome c oxidase have been studied by stopped-flow spectroscopy following chemical modification of the CuA site with mercurials. In this derivative CuA is no longer reducible by cytochrome c while cytochrome alpha may accept electrons from the latter with rates comparable to the native enzyme. The results indicate that CuA is not the exclusive electron entry site in cytochrome c oxidase.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
