New enantiopure aniline-containing amino alcohols are directly derived from trans-(R,R)-2-(2-nitrophenyl)-3-phenyloxirane,by alternative regioselective double reductions. Subsequent selective alkylation procedures and derivatizations provide a rapid and high-yielding access to different chiral ligands, bases, and benzoxazines, without loss of optical purity.

New aniline containing aminoalcohols from trans (R,R) 2-(2-nitrophenyl)-3-phenyloxirane as useful intermediates for the synthesis of chiral ligands, bases and benzoxazines / SOLLADIE' CAVALLO, A; Bonini, Carlo Cesare; Ostuni, V; DI BLASIO, N; Lupattelli, Paolo. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 71:(2006), pp. 9891-9894. [10.1021/jo0617969]

New aniline containing aminoalcohols from trans (R,R) 2-(2-nitrophenyl)-3-phenyloxirane as useful intermediates for the synthesis of chiral ligands, bases and benzoxazines

BONINI, Carlo Cesare;LUPATTELLI, Paolo
2006

Abstract

New enantiopure aniline-containing amino alcohols are directly derived from trans-(R,R)-2-(2-nitrophenyl)-3-phenyloxirane,by alternative regioselective double reductions. Subsequent selective alkylation procedures and derivatizations provide a rapid and high-yielding access to different chiral ligands, bases, and benzoxazines, without loss of optical purity.
2006
01 Pubblicazione su rivista::01a Articolo in rivista
New aniline containing aminoalcohols from trans (R,R) 2-(2-nitrophenyl)-3-phenyloxirane as useful intermediates for the synthesis of chiral ligands, bases and benzoxazines / SOLLADIE' CAVALLO, A; Bonini, Carlo Cesare; Ostuni, V; DI BLASIO, N; Lupattelli, Paolo. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 71:(2006), pp. 9891-9894. [10.1021/jo0617969]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1653080
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