Smoking habits represent a cardiovascular risk factor with tremendous impact on health. Other than damaging differentiated and functional cells of the cardiovascular system, they also negatively affect reparative mechanisms, such as those involved in cardiac fibrosis and in endothelial progenitor cell (EPC) activation. In recent years, alternative smoking devices, dubbed modified tobacco risk products (MRPs), have been introduced, but their precise impact on human health is still under evaluation. Also, they have not been characterized yet about the possible negative effects on cardiovascular reparative and regenerative cells, such as EPCs or pluripotent stem cells. In this perspective, we critically review the still scarce available data on the effects of MRPs on molecular and cellular mechanisms of cardiovascular repair and regeneration.

Modified risk tobacco products and cardiovascular repair. Still very smoky / Cozzolino, Claudia; Picchio, Vittorio; Floris, Erica; Pagano, Francesca; Saade, Wael; Peruzzi, Mariangela; Frati, Giacomo; Chimenti, Isotta. - In: CURRENT STEM CELL RESEARCH & THERAPY. - ISSN 1574-888X. - 18:4(2023), pp. 440-444. [10.2174/1574888X17666220802142532]

Modified risk tobacco products and cardiovascular repair. Still very smoky

Cozzolino, Claudia;Picchio, Vittorio;Floris, Erica;Saade, Wael;Peruzzi, Mariangela;Frati, Giacomo;Chimenti, Isotta
Ultimo
2023

Abstract

Smoking habits represent a cardiovascular risk factor with tremendous impact on health. Other than damaging differentiated and functional cells of the cardiovascular system, they also negatively affect reparative mechanisms, such as those involved in cardiac fibrosis and in endothelial progenitor cell (EPC) activation. In recent years, alternative smoking devices, dubbed modified tobacco risk products (MRPs), have been introduced, but their precise impact on human health is still under evaluation. Also, they have not been characterized yet about the possible negative effects on cardiovascular reparative and regenerative cells, such as EPCs or pluripotent stem cells. In this perspective, we critically review the still scarce available data on the effects of MRPs on molecular and cellular mechanisms of cardiovascular repair and regeneration.
2023
Endothelial progenitor cells; cardiac fibrosis; cardiovascular regeneration.; electronic cigarettes; modified risk products; pluripotent stem cells
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Modified risk tobacco products and cardiovascular repair. Still very smoky / Cozzolino, Claudia; Picchio, Vittorio; Floris, Erica; Pagano, Francesca; Saade, Wael; Peruzzi, Mariangela; Frati, Giacomo; Chimenti, Isotta. - In: CURRENT STEM CELL RESEARCH & THERAPY. - ISSN 1574-888X. - 18:4(2023), pp. 440-444. [10.2174/1574888X17666220802142532]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1652937
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