Systemic sclerosis (SSc) is characterized by a complex etiopathogenesis encompassing both host genetic and environmental -infectious/toxic- factors responsible for altered fibrogenesis and diffuse microangiopathy. A wide spectrum of clinical phenotypes may be observed in patients' populations from different geographical areas. We investigated the prevalence of specific clinical and serological phenotypes in patients with definite SSc enrolled at tertiary referral centres in different Italian geographical macro-areas. The observed findings were compared with those reported in the world literature.
Geographical heterogeneity of clinical and serological phenotypes of systemic sclerosis observed at tertiary referral centres. the experience of the Italian SIR-SPRING registry and review of the world literature / Ferri, Clodoveo; De Angelis, Rossella; Giuggioli, Dilia; Bajocchi, Gianluigi; Dagna, Lorenzo; Zanframundo, Giovanni; Foti, Rosario; Cacciapaglia, Fabio; Cuomo, Giovanna; Ariani, Alarico; Rosato, Edoardo; Guiducci, Serena; Girelli, Francesco; Riccieri, Valeria; Zanatta, Elisabetta; Bosello, Silvia; Cavazzana, Ilaria; Ingegnoli, Francesca; De Santis, Maria; Murdaca, Giuseppe; Abignano, Giuseppina; Romeo, Nicoletta; Della Rossa, Alessandra; Caminiti, Maurizio; Iuliano, Annamaria; Ciano, Giovanni; Beretta, Lorenzo; Bagnato, Gianluca; Lubrano, Ennio; De Andres, Ilenia; Giollo, Alessandro; Saracco, Marta; Agnes, Cecilia; Lumetti, Federica; Spinella, Amelia; Magnani, Luca; Campochiaro, Corrado; De Luca, Giacomo; Codullo, Veronica; Visalli, Elisa; Masini, Francesco; Gigante, Antonietta; Bellando-Randone, Silvia; Pellegrino, Greta; Pigatto, Erika; Lazzaroni, Maria Grazia; Franceschini, Franco; Generali, Elena; Mennillo, Gianna; Barsotti, Simone; Mariano, Giuseppa Pagano; Calabrese, Francesca; Furini, Federica; Vultaggio, Licia; Parisi, Simone; Peroni, Clara Lisa; Rozza, Davide; Zanetti, Anna; Carrara, Greta; Landolfi, Giampiero; Scirè, Carlo Alberto; Bianchi, Gerolamo; Fusaro, Enrico; Sebastiani, Gian Domenico; Govoni, Marcello; D'Angelo, Salvatore; Cozzi, Franco; Doria, Andrea; Iannone, Florenzo; Salvarani, Carlo; Matucci-Cerinic, Marco. - In: AUTOIMMUNITY REVIEWS. - ISSN 1873-0183. - 21:10(2022). [10.1016/j.autrev.2022.103159]
Geographical heterogeneity of clinical and serological phenotypes of systemic sclerosis observed at tertiary referral centres. the experience of the Italian SIR-SPRING registry and review of the world literature
Rosato, Edoardo;Riccieri, Valeria;Gigante, Antonietta;Pellegrino, Greta;
2022
Abstract
Systemic sclerosis (SSc) is characterized by a complex etiopathogenesis encompassing both host genetic and environmental -infectious/toxic- factors responsible for altered fibrogenesis and diffuse microangiopathy. A wide spectrum of clinical phenotypes may be observed in patients' populations from different geographical areas. We investigated the prevalence of specific clinical and serological phenotypes in patients with definite SSc enrolled at tertiary referral centres in different Italian geographical macro-areas. The observed findings were compared with those reported in the world literature.| File | Dimensione | Formato | |
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