Surgery is the mainstay of treatment in the management of early-stage cervical cancer. Until the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, minimally invasive radical hysterectomy was the recommended approach to treat patients with early-stage disease. The results of the LACC trial questioned the adoption of minimally invasive surgery in cervical cancer. In comparison with the open approach, minimally invasive surgery correlated with worse disease-free and cancer-specific survival. Similarly, other retrospective studies highlighted this correlation, thus corroborating the results of the LACC trials. In the present review, we evaluated current evidence and further prospective of the adoption of minimally invasive radical hysterectomy in cervical cancer. Moreover, we sought to assess some unsolved issues regarding the role of minimally invasive surgery in early-stage cervical cancer patients.
Assessing the role of minimally invasive radical hysterectomy for early-stage cervical cancer / Bogani, Giorgio; Di Donato, Violante; Muzii, Ludovico; Casarin, Jvan; Ghezzi, Fabio; Malzoni, Mario; Greggi, Stefano; Landoni, Fabio; Bazzurini, Luca; Zanagnolo, Vanna; Multinu, Francesco; Angioli, Roberto; Plotti, Francesco; Caruso, Giuseppe; Fischetti, Margherita; Ferrandina, Gabriella; Palaia, Innocenza; Benedetti Panici, Pierluigi; Scambia, Giovanni; Raspagliesi, Francesco. - In: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY. - ISSN 1872-7654. - 275:(2022), pp. 64-69. [10.1016/j.ejogrb.2022.06.004]
Assessing the role of minimally invasive radical hysterectomy for early-stage cervical cancer
Bogani, Giorgio;Di Donato, Violante;Muzii, Ludovico;Caruso, Giuseppe;Fischetti, Margherita;Palaia, Innocenza;Benedetti Panici, Pierluigi;
2022
Abstract
Surgery is the mainstay of treatment in the management of early-stage cervical cancer. Until the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, minimally invasive radical hysterectomy was the recommended approach to treat patients with early-stage disease. The results of the LACC trial questioned the adoption of minimally invasive surgery in cervical cancer. In comparison with the open approach, minimally invasive surgery correlated with worse disease-free and cancer-specific survival. Similarly, other retrospective studies highlighted this correlation, thus corroborating the results of the LACC trials. In the present review, we evaluated current evidence and further prospective of the adoption of minimally invasive radical hysterectomy in cervical cancer. Moreover, we sought to assess some unsolved issues regarding the role of minimally invasive surgery in early-stage cervical cancer patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
