Translation of electron FLASH radiotherapy in clinical practice requires the use of high energy accelerators to treat deep tumours and Very High Electron Energy (VHEE) could represent a valid technique to achieve this goal. In this scenario, a VHEE FLASH linac is under study at the University La Sapienza of Rome (Italy) in collaboration with the Italian Institute for Nuclear Research (INFN) and the Institut Curie (France). Here we present the preliminary results of a compact C-band system aiming to reach an high accelerating gradient and an high pulse current necessary to deliver high dose per pulse and ultra-high dose rate required for FLASH effect. We propose a system composed of a low energy high current injector linac followed by a modular section of high accelerating gradient structures. CST code is used to define the required LINAC’s RF parameters and beam dynamics simulations are performed using TSTEP and ASTRA.

Proposal af a VHEE LINAC for FLASH radiotherapy / Giuliano, L.; Bosco, F.; Carillo, M.; Arcangelis, D. De.; Ficcadenti, L.; De Gregorio, D. Francescone. A.; Franciosini, G.; Migliorati, M.; Mostacci, A.; Palumbo, L.; Patera, V.; Alesini, A. Sarti D.; Behtouei, M.; Faillace, L.; Gallo, A.; Spataro, B.; Vannozzi, A.; Cirrone, P.; Cuttone, G.; Torrisi, G.; Bisogni, M. G.; Pensavalle, J. H.; Martino, F. Di.; Favaudon, V.; Heinrich, S.; Patriarca, A.. - (2022). ((Intervento presentato al convegno IPAC22 tenutosi a BANGKOK THAILAND [10.18429/JACoW-IPAC2022-THPOTK054].

Proposal af a VHEE LINAC for FLASH radiotherapy

D. De Arcangelis;L. Ficcadenti;G. Franciosini;A. Mostacci;M. Behtouei;L. Faillace;B. Spataro;A. Vannozzi;
2022

Abstract

Translation of electron FLASH radiotherapy in clinical practice requires the use of high energy accelerators to treat deep tumours and Very High Electron Energy (VHEE) could represent a valid technique to achieve this goal. In this scenario, a VHEE FLASH linac is under study at the University La Sapienza of Rome (Italy) in collaboration with the Italian Institute for Nuclear Research (INFN) and the Institut Curie (France). Here we present the preliminary results of a compact C-band system aiming to reach an high accelerating gradient and an high pulse current necessary to deliver high dose per pulse and ultra-high dose rate required for FLASH effect. We propose a system composed of a low energy high current injector linac followed by a modular section of high accelerating gradient structures. CST code is used to define the required LINAC’s RF parameters and beam dynamics simulations are performed using TSTEP and ASTRA.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1651285
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