Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to justify this step. In this “opinion article” we propose a role for intron sequences in stabilizing gene duplication by limiting and reducing the identity of the gene sequence between the two duplicated copies. A review of the topic and a detailed hypothesis are presented.

Can Introns Stabilize Gene Duplication? / Micheli, Gioacchino; Camilloni, Giorgio. - In: BIOLOGY. - ISSN 2079-7737. - 11:6(2022), p. 941. [10.3390/biology11060941]

Can Introns Stabilize Gene Duplication?

Giorgio Camilloni
2022

Abstract

Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to justify this step. In this “opinion article” we propose a role for intron sequences in stabilizing gene duplication by limiting and reducing the identity of the gene sequence between the two duplicated copies. A review of the topic and a detailed hypothesis are presented.
2022
gene duplication; introns; genome evolution
01 Pubblicazione su rivista::01a Articolo in rivista
Can Introns Stabilize Gene Duplication? / Micheli, Gioacchino; Camilloni, Giorgio. - In: BIOLOGY. - ISSN 2079-7737. - 11:6(2022), p. 941. [10.3390/biology11060941]
File allegati a questo prodotto
File Dimensione Formato  
Micheli_Introns_2022.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 467 kB
Formato Adobe PDF
467 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1650845
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact