Mutations in the JAK2, MPL and CALR driver genes are reported in over 90% of adults with BCR-ABL1-negative chronic myeloproliferative neoplasms (MPNs) and in 22-40% of children, where inherited forms, such as familial erythrocytosis (FE) and hereditary thrombocytosis (HT), are common. Next Generation Sequencing (NGS) is useful to identify clonal markers, other than those found using standardized methods.
P981: NEXT GENERATION SEQUENCING (NGS): AN IMPORTANT TOOL TO CHARACTERIZE MYELOPROLIFERATIVE DISEASES IN CHILDREN / Bianchi, S.; Palumbo, Giovanna; Filipponi, V.; Monaco, Nicola; Pileggi, G.; Maglione, R.; Rousseau, M.; Moleti, M. L.; Giona, F.. - In: HEMASPHERE. - ISSN 2572-9241. - 6:(2022), pp. 871-872. [10.1097/01.HS9.0000846792.99847.f4]
P981: NEXT GENERATION SEQUENCING (NGS): AN IMPORTANT TOOL TO CHARACTERIZE MYELOPROLIFERATIVE DISEASES IN CHILDREN
Bianchi, S.;Palumbo, Giovanna;Filipponi, V.;Monaco, Nicola;Pileggi, G.;Maglione, R.;Rousseau, M.;Moleti, M. L.;Giona, F.
2022
Abstract
Mutations in the JAK2, MPL and CALR driver genes are reported in over 90% of adults with BCR-ABL1-negative chronic myeloproliferative neoplasms (MPNs) and in 22-40% of children, where inherited forms, such as familial erythrocytosis (FE) and hereditary thrombocytosis (HT), are common. Next Generation Sequencing (NGS) is useful to identify clonal markers, other than those found using standardized methods.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
