Nitric oxide (NO) has emerged as an important cytotoxic and cytostatic effector for a number of pathogens, including viruses, bacteria, fungi, and parasites. When the microbicidal effect of NO occurs, the NO-mediated S-nitrosylation of cysteine containing proteins (e.g., cysteine proteases) appears to be a common and widespread mechanism. This overview concerns parasitic cysteine proteases as NO targets, providing molecular bases for the parasiticidal effect of NO.

Molecular bases for the anti-parasitic effect of NO (Review) / Colasanti, M.; Gradoni, L.; Mattu, M.; Persichini, T.; Salvati, L.; Venturini, G.; Ascenzi, P.. - In: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. - ISSN 1107-3756. - 9:(2002), pp. 131-134. [10.3892/ijmm.9.2.131]

Molecular bases for the anti-parasitic effect of NO (Review)

Salvati L.;
2002

Abstract

Nitric oxide (NO) has emerged as an important cytotoxic and cytostatic effector for a number of pathogens, including viruses, bacteria, fungi, and parasites. When the microbicidal effect of NO occurs, the NO-mediated S-nitrosylation of cysteine containing proteins (e.g., cysteine proteases) appears to be a common and widespread mechanism. This overview concerns parasitic cysteine proteases as NO targets, providing molecular bases for the parasiticidal effect of NO.
2002
01 Pubblicazione su rivista::01a Articolo in rivista
Molecular bases for the anti-parasitic effect of NO (Review) / Colasanti, M.; Gradoni, L.; Mattu, M.; Persichini, T.; Salvati, L.; Venturini, G.; Ascenzi, P.. - In: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. - ISSN 1107-3756. - 9:(2002), pp. 131-134. [10.3892/ijmm.9.2.131]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1646997
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