ASSESSMENT OF VARIOUS LIPID RICH DIETS FOR THE INDUCTION OF DYSLIPIDEMIA IN ANIMAL MODEL "AN EXPERIMENTAL STUDY"

Objectives: The objective of this study was to evaluate various lipid rich diets for the induction ofdyslipidemia in animal model.Methods: This was an experimental study conducted on 42 Wistar albino rats. Animals wererandomly divided into 7 groups on the basis of administration of various oils, including Canola oil,Coconut oil and Banaspati ghee alone and in combination of any two of them simultaneously; whileone group served as control was administered normal saline. Baseline body weights of all groups ofanimals were measured at the start of the study. At the end of 4 weeks of lipid diets, body weight ofall groups of animal groups was measured again and their blood was drawn through cardiacpuncture for the assessment of TC, LDL-C, HDL, TGs.Results: Amongst all the groups, Group F (Banaspati ghee + Coconut oil) showed maximumincrease in LDL-C, TC,TGs, body weight and decrease in HDL-C (p-value <0.05) in comparison tocontrol.Conclusion: It is concluded that the combination of Banaspati ghee and Coconut oil may prove tobe most effective lipid diet for the induction of dyslipidemia in animal model.