The human teeth and oral cavity harbor various populations of mesenchymal stem cells (MSCs), so called dental-derived stem cells (D-dSCs) with self-renewing and multilineage differentiation capabilities. D-dSCs properties involves a strong paracrine component resulting from the high levels of bioactive molecules they secrete in response to the local microenvironment. Altogether, this viewpoint develops a general picture of current innovative strategies to employ D-dSCs combined with biomaterials and bioactive factors for regenerative medicine purposes, and offers information regarding the available scientific data and possible applications.
Dental-derived stem cells and biowaste biomaterials: what’s next in bone regenerative medicine applications / Cosola, M. D.; Cantore, S.; Balzanelli, M. G.; Isacco, C. G.; Nguyen, K. C. D.; Saini, R.; Malcangi, A.; Tumedei, M.; Ambrosino, M.; Mancini, A.; Scacco, S.; Nocini, R.; Santacroce, L.; Ballini, A.; Brauner, E.. - In: BIOCELL. - ISSN 0327-9545. - 46:4(2022), pp. 923-929. [10.32604/biocell.2022.018409]
Dental-derived stem cells and biowaste biomaterials: what’s next in bone regenerative medicine applications
Brauner E.Ultimo
2022
Abstract
The human teeth and oral cavity harbor various populations of mesenchymal stem cells (MSCs), so called dental-derived stem cells (D-dSCs) with self-renewing and multilineage differentiation capabilities. D-dSCs properties involves a strong paracrine component resulting from the high levels of bioactive molecules they secrete in response to the local microenvironment. Altogether, this viewpoint develops a general picture of current innovative strategies to employ D-dSCs combined with biomaterials and bioactive factors for regenerative medicine purposes, and offers information regarding the available scientific data and possible applications.| File | Dimensione | Formato | |
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Note: https://www.techscience.com/biocell/v46n4/45995
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