A 72‐year‐old man came to the attention of the clinicians with a long history of diarrhea. The gastroenterologist performed a colonoscopy that revealed diverticular disease in colon and sigma and the presence of an exophytic lesion measuring 4 cm, located at 12 cm from the anals margin and that was biopsied. Histologically, it was a tubulo‐villous adenoma with low grade dysplasia. Computed tomography (CT) scan confirmed the diverticular disease but not the exophytic lesion of the rectum that was evident, instead, on magnetic resonance imaging of the abdomen. No lymph nodes adenomegalies were evident. The patient's medical history did not include any other pathology. A week later, the lesion was removed endoscopically with diathermic loop. Numerous fragments, measuring 5 × 4 cm, were examined. It was concluded that, in the context of a rectal tubulovillous adenoma with high grade dysplasia, a neuroendocrine ‘microcarcinoma’ was detected, that was confined to the mucosa. In the present case the diagnosis was made just by chance, because the adenomatous lesion was voluminous and it had caused diarrhea.

An incidental rectal neuroendocrine microcarcinoma (‘micro-NEC’) coexistent with a high grade adenoma / Guadagno, E.; Cervasio, M.; De Rosa, F.; Modica, R.; Faggiano, A.; Del Basso De Caro, M.. - In: PATHOLOGY INTERNATIONAL. - ISSN 1320-5463. - 70:5(2020), pp. 300-302. [10.1111/pin.12916]

An incidental rectal neuroendocrine microcarcinoma (‘micro-NEC’) coexistent with a high grade adenoma

Faggiano A.;
2020

Abstract

A 72‐year‐old man came to the attention of the clinicians with a long history of diarrhea. The gastroenterologist performed a colonoscopy that revealed diverticular disease in colon and sigma and the presence of an exophytic lesion measuring 4 cm, located at 12 cm from the anals margin and that was biopsied. Histologically, it was a tubulo‐villous adenoma with low grade dysplasia. Computed tomography (CT) scan confirmed the diverticular disease but not the exophytic lesion of the rectum that was evident, instead, on magnetic resonance imaging of the abdomen. No lymph nodes adenomegalies were evident. The patient's medical history did not include any other pathology. A week later, the lesion was removed endoscopically with diathermic loop. Numerous fragments, measuring 5 × 4 cm, were examined. It was concluded that, in the context of a rectal tubulovillous adenoma with high grade dysplasia, a neuroendocrine ‘microcarcinoma’ was detected, that was confined to the mucosa. In the present case the diagnosis was made just by chance, because the adenomatous lesion was voluminous and it had caused diarrhea.
File allegati a questo prodotto
File Dimensione Formato  
Guadagno_An-incidental-rectal_2020.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 820.51 kB
Formato Adobe PDF
820.51 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/1633344
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact