Systemic therapy with androgen deprivation (ADT) has been for long time the main treatment for advanced prostate cancer (PC), and for those men with early-stage PC who experience biochemical progression after primary treatments. A hormone sensitive (HS) phase of PC is always followed by the development of castration resistant (CRPC) growth and this progression is in part dependent on the use of ADT in the first period. According to the European Association of Urology (EAU) guidelines, CRPC can be defined as castrate serum testosterone (<50 ng/dL or 1.7 nmol/L) plus either biochemical or radiological progression.
Comment on: Androgen receptor axis-targeted agents for non-metastatic castration-resistant prostate cancer impact on overall survival and safety profile: an updated systematic review and meta-analysis / Salciccia, Stefano; Sciarra, Alessandro; Cattarino, Susanna; Mariotti, Gianna; Bevilacqua, Giulio; Gentilucci, Alessandro. - In: MINERVA UROLOGY AND NEPHROLOGY. - ISSN 2724-6051. - 74(3):(2022). [10.23736/S2724-6051.22.04948-5]
Comment on: Androgen receptor axis-targeted agents for non-metastatic castration-resistant prostate cancer impact on overall survival and safety profile: an updated systematic review and meta-analysis
Stefano Salciccia;Alessandro Sciarra;Giulio Bevilacqua;Alessandro Gentilucci
2022
Abstract
Systemic therapy with androgen deprivation (ADT) has been for long time the main treatment for advanced prostate cancer (PC), and for those men with early-stage PC who experience biochemical progression after primary treatments. A hormone sensitive (HS) phase of PC is always followed by the development of castration resistant (CRPC) growth and this progression is in part dependent on the use of ADT in the first period. According to the European Association of Urology (EAU) guidelines, CRPC can be defined as castrate serum testosterone (<50 ng/dL or 1.7 nmol/L) plus either biochemical or radiological progression.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
