A cohort of 39 patients with genetically confirmed DM1 and able to walk without any support was evaluated. A quantitative muscle test and a six-minute walk test (6MWT) were performed. In addition, 13 patients and 11 healthy controls (HC) underwent the 10-meter Walk Test while wearing kinematic sensors at the legs. An amplitude analysis (AR) and a power spectral density analysis (PR) of the ankle angles during gait were performed, conducting to a severity index (Norm2). Descriptive statistics, t-test, and correlation test were analyzed.
A clinical and kinematic evaluation of foot drop in myotonic dystrophy type I: A pilot study / Frezza, Erica; Manoni, Alessandro; Errico, Vito; Rota, Rosario; Greco, Giulia; Goglia, Mariangela; Irrera, Fernanda; Saggio, Giovanni; Massa, Roberto. - In: JOURNAL OF THE NEUROLOGICAL SCIENCES. - ISSN 0022-510X. - 429:(2021). [10.1016/j.jns.2021.119766]
A clinical and kinematic evaluation of foot drop in myotonic dystrophy type I: A pilot study
Manoni, Alessandro;Irrera, Fernanda;
2021
Abstract
A cohort of 39 patients with genetically confirmed DM1 and able to walk without any support was evaluated. A quantitative muscle test and a six-minute walk test (6MWT) were performed. In addition, 13 patients and 11 healthy controls (HC) underwent the 10-meter Walk Test while wearing kinematic sensors at the legs. An amplitude analysis (AR) and a power spectral density analysis (PR) of the ankle angles during gait were performed, conducting to a severity index (Norm2). Descriptive statistics, t-test, and correlation test were analyzed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
