We have analyzed the localization and the dependence upon superhelical density of the DNA sites which modify their conformation under torsional strain in a mouse Ig L kappa gene. The conformational variations occur on DNA sites which have been defined as protein interaction sites and consensus sequence motifs: the 5'-upstream regulatory decanucleotides, the TATA sequence, the consensus heptanucleotides of the J recombinational sequences.
DNA conformational variations in the in vitro torsionally strained Ig kappa light chain gene localize on consensus sequences / Venditti, Sabrina Donatella Sonia; Caserta, M; DI MAURO, Ernesto; Camilloni, Giorgio. - In: BIOCHIMICA ET BIOPHYSICA ACTA. - ISSN 0006-3002. - STAMPA. - 951:(1988), pp. 139-148. [10.1016/0167-4781(88)90034-6]
DNA conformational variations in the in vitro torsionally strained Ig kappa light chain gene localize on consensus sequences.
VENDITTI, Sabrina Donatella Sonia;DI MAURO, Ernesto;CAMILLONI, Giorgio
1988
Abstract
We have analyzed the localization and the dependence upon superhelical density of the DNA sites which modify their conformation under torsional strain in a mouse Ig L kappa gene. The conformational variations occur on DNA sites which have been defined as protein interaction sites and consensus sequence motifs: the 5'-upstream regulatory decanucleotides, the TATA sequence, the consensus heptanucleotides of the J recombinational sequences.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
