Background: Organ donation (OD) remains the only therapeutic option for end-stage disease in some cases. Unfortunately, the gap between donors and recipients is still substantial. Trauma patients represent a potential yet underestimated pool of organ donors. In this article, we present our data on OD after damage control strategy (DCS). Materials and Methods: A retrospective, observational cohort study was conducted through a complete revision of data of consecutive adult trauma patients (>18 years old) who underwent OD after DCS between January 2018 and May 2021. Four subgroups were created [Liver (Li), Lungs (Lu), Heart (H), Kidneys (K)] to compare variables between those who donated the organ of interest and those who did not. Results: Thirty-six patients underwent OD after DCS. Six patients (16.7%) were excluded: 2(5.6%) for missing data about admission; 4(11.1%) didn’t receive DCS. Mean ISS was 47.2 (SD ± 17.4). Number of donated organs was 113 with an organs/patient ratio of 3.8. The functional response rate was 91.2%. Ten organs (8.8%) had primary nonfunction after transplantation: 2/15 hearts (13.3%), 1/28 livers (3.6%), 4/53 kidneys (7.5%) and 3/5 pancreases (60%). No lung primary nonfunction were registered. Complete results of subgroup analysis are reported in supplementary materials. Conclusion: Organ donation should be considered a possible outcome in any trauma patient. Aggressive damage control strategy doesn’t affect the functional response rate of transplanted organs.

Organ Donation after Damage Control Strategy in Trauma Patients: Experience from First Level Trauma Center in Italy / Altomare, M.; Bekhor, S. S.; Cioffi, S. P. B.; Sacchi, M.; Renzi, F.; Spota, A.; Bini, R.; Ambrogi, F.; Pozzi, F.; Chieregato, A.; Chiara, O.; Cimbanassi, S.. - In: LIFE. - ISSN 2075-1729. - 12:2(2022), p. 214. [10.3390/life12020214]

Organ Donation after Damage Control Strategy in Trauma Patients: Experience from First Level Trauma Center in Italy

Altomare M.;Cioffi S. P. B.;
2022

Abstract

Background: Organ donation (OD) remains the only therapeutic option for end-stage disease in some cases. Unfortunately, the gap between donors and recipients is still substantial. Trauma patients represent a potential yet underestimated pool of organ donors. In this article, we present our data on OD after damage control strategy (DCS). Materials and Methods: A retrospective, observational cohort study was conducted through a complete revision of data of consecutive adult trauma patients (>18 years old) who underwent OD after DCS between January 2018 and May 2021. Four subgroups were created [Liver (Li), Lungs (Lu), Heart (H), Kidneys (K)] to compare variables between those who donated the organ of interest and those who did not. Results: Thirty-six patients underwent OD after DCS. Six patients (16.7%) were excluded: 2(5.6%) for missing data about admission; 4(11.1%) didn’t receive DCS. Mean ISS was 47.2 (SD ± 17.4). Number of donated organs was 113 with an organs/patient ratio of 3.8. The functional response rate was 91.2%. Ten organs (8.8%) had primary nonfunction after transplantation: 2/15 hearts (13.3%), 1/28 livers (3.6%), 4/53 kidneys (7.5%) and 3/5 pancreases (60%). No lung primary nonfunction were registered. Complete results of subgroup analysis are reported in supplementary materials. Conclusion: Organ donation should be considered a possible outcome in any trauma patient. Aggressive damage control strategy doesn’t affect the functional response rate of transplanted organs.
2022
Damage control; Damage control surgery; Organ donation; Trauma; Trauma donors
01 Pubblicazione su rivista::01a Articolo in rivista
Organ Donation after Damage Control Strategy in Trauma Patients: Experience from First Level Trauma Center in Italy / Altomare, M.; Bekhor, S. S.; Cioffi, S. P. B.; Sacchi, M.; Renzi, F.; Spota, A.; Bini, R.; Ambrogi, F.; Pozzi, F.; Chieregato, A.; Chiara, O.; Cimbanassi, S.. - In: LIFE. - ISSN 2075-1729. - 12:2(2022), p. 214. [10.3390/life12020214]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1629656
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