Background: There is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts. Materials and methods: This analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien–Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups. Results: In total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07). Conclusions: This global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts.

30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data / Singhal, R.; Cardoso, V. R.; Wiggins, T.; Super, J.; Ludwig, C.; Gkoutos, G. V.; Mahawar, K.; Pedziwiatr, M.; Major, P.; Zarzycki, P.; Pantelis, A.; Lapatsanis, D. P.; Stravodimos, G.; Matthys, C.; Focquet, M.; Vleeschouwers, W.; Spaventa, A. G.; Zerrweck, C.; Vitiello, A.; Berardi, G.; Musella, M.; Sanchez-Meza, A.; Cantu, F. J.; Mora, F.; Cantu, M. A.; Katakwar, A.; Reddy, D. N.; Elmaleh, H.; Hassan, M.; Elghandour, A.; Elbanna, M.; Osman, A.; Khan, A.; Layani, L.; Kiran, N.; Velikorechin, A.; Solovyeva, M.; Melali, H.; Shahabi, S.; Agrawal, A.; Shrivastava, A.; Sharma, A.; Narwaria, B.; Narwaria, M.; Raziel, A.; Sakran, N.; Susmallian, S.; Karagoz, L.; Akbaba, M.; Piskin, S. Z.; Balta, A. Z.; Senol, Z.; Manno, E.; Iovino, M. G.; Osman, A.; Qassem, M.; Arana-Garza, S.; Povoas, H. P.; Vilas-Boas, M. L.; Naumann, D.; Li, A.; Ammori, B. J.; Balamoun, H.; Salman, M.; Nasta, A. M.; Goel, R.; Sanchez-Aguilar, H.; Herrera, M. F.; Abou-mrad, A.; Cloix, L.; Mazzini, G. S.; Kristem, L.; Lazaro, A.; Campos, J.; Bernardo, J.; Gonzalez, J.; Trindade, C.; Viveiros, O.; Ribeiro, R.; Goitein, D.; Hazzan, D.; Segev, L.; Beck, T.; Reyes, H.; Monterrubio, J.; Garcia, P.; Benois, M.; Kassir, R.; Contine, A.; Elshafei, M.; Aktas, S.; Weiner, S.; Heidsieck, T.; Level, L.; Pinango, S.; Ortega, P. M.; Moncada, R.; Valenti, V.; Vlahovic, I.; Boras, Z.; Liagre, A.; Martini, F.; Juglard, G.; Motwani, M.; Saggu, S. S.; Momani, H. A.; Lopez, L. A. A.; Cortez, M. A. C.; Zavala, R. A.; D'Haese RN, C.; Kempeneers, I.; Himpens, J.; Lazzati, A.; Paolino, L.; Bathaei, S.; Bedirli, A.; Yavuz, A.; Buyukkasap, C.; Ozaydin, S.; Kwiatkowski, A.; Bartosiak, K.; Waledziak, M.; Santonicola, A.; Angrisani, L.; Iovino, P.; Palma, R.; Iossa, A.; Boru Cristian, Eugeniu.; De Angelis, F.; Silecchia, G.; Hussain, A.; Balchandra, S.; Coltell, I. B.; Perez, J. L.; Bohra, A.; Awan, A. K.; Madhok, B.; Leeder, P. C.; Awad, S.; Al-Khyatt, W.; Shoma, A.; Elghadban, H.; Ghareeb, S.; Mathews, B.; Kurian, M.; Larentzakis, A.; Vrakopoulou, G. Z.; Albanopoulos, K.; Bozdag, A.; Lale, A.; Kirkil, C.; Dincer, M.; Bashir, A.; Haddad, A.; Hijleh, L. A.; Zilberstein, B.; de Marchi, D. D.; Souza, W. P.; Broden, C. M.; Gislason, H.; Shah, K.; Ambrosi, A.; Pavone, G.; Tartaglia, N.; Kona, S. L. K.; Kalyan, K.; Perez, C. E. G.; Botero, M. A. F.; Covic, A.; Timofte, D.; Maxim, M.; Faraj, D.; Tseng, L.; Liem, R.; Oren, G.; Dilektasli, E.; Yalcin, I.; Almukhtar, H.; Hadad, M. A.; Mohan, R.; Arora, N.; Bedi, D.; Rives-Lange, C.; Chevallier, J. -M.; Poghosyan, T.; Sebbag, H.; Zinai, L.; Khaldi, S.; Mauchien, C.; Mazza, D.; Dinescu, G.; Rea, B.; Perez-Galaz, F.; Zavala, L.; Besa, A.; Curell, A.; Balibrea, J. M.; Vaz, C.; Galindo, L.; Silva, N.; Caballero, J. L. E.; Sebastian, S. O.; Marchesini, J. C. D.; da Fonseca Pereira, R. A.; Sobottka, W. H.; Fiolo, F. E.; Turchi, M.; Coelho, A. C. J.; Zacaron, A. L.; Barbosa, A.; Quinino, R.; Menaldi, G.; Paleari, N.; Martinez-Duartez, P.; de Esparza, G. M. A. R.; Esteban, V. S.; Torres, A.; Garcia-Galocha, J. L.; Josa, M.; Pacheco-Garcia, J. M.; Mayo-Ossorio, M. A.; Chowbey, P.; Soni, V.; de Vasconcelos Cunha, H. A.; Castilho, M. V.; Ferreira, R. M. A.; Barreiro, T. A.; Charalabopoulos, A.; Sdralis, E.; Davakis, S.; Bomans, B.; Dapri, G.; Van Belle, K.; Takieddine, M.; Vaneukem, P.; Karaca, E. S. A.; Karaca, F. C.; Sumer, A.; Peksen, C.; Savas, O. A.; Chousleb, E.; Elmokayed, F.; Fakhereldin, I.; Aboshanab, H. M.; Swelium, T.; Gudal, A.; Gamloo, L.; Ugale, A.; Ugale, S.; Boeker, C.; Reetz, C.; Hakami, I. A.; Mall, J.; Alexandrou, A.; Baili, E.; Bodnar, Z.; Maleckas, A.; Gudaityte, R.; Guldogan, C. E.; Gundogdu, E.; Ozmen, M. M.; Thakkar, D.; Dukkipati, N.; Shah, P. S.; Shah, S. S.; Shah, S. S.; Adil, M. T.; Jambulingam, P.; Mamidanna, R.; Whitelaw, D.; Adil, M. T.; Jain, V.; Veetil, D. K.; Wadhawan, R.; Torres, A.; Torres, M.; Tinoco, T.; Leclercq, W.; Romeijn, M.; van de Pas, K.; Alkhazraji, A. K.; Taha, S. A.; Ustun, M.; Yigit, T.; Inam, A.; Burhanulhaq, M.; Pazouki, A.; Eghbali, F.; Kermansaravi, M.; Jazi, A. H. D.; Mahmoudieh, M.; Mogharehabed, N.; Tsiotos, G.; Stamou, K.; Rodriguez, F. J. B.; Navarro, M. A. R.; Torres, O. M.; Martinez, S. L.; Tamez, E. R. M.; Cornejo, G. A. M.; Flores, J. E. G.; Mohammed, D. A.; Elfawal, M. H.; Shabbir, A.; Guowei, K.; So, J. B.; Kaplan, E. T.; Kaplan, M.; Kaplan, T.; Pham, D. T.; Rana, G.; Kappus, M.; Gadani, R.; Kahitan, M.; Pokharel, K.; Osborne, A.; Pournaras, D.; Hewes, J.; Napolitano, E.; Chiappetta, S.; Bottino, V.; Dorado, E.; Schoettler, A.; Gaertner, D.; Fedtke, K.; Aguilar-Espinosa, F.; Aceves-Lozano, S.; Balani, A.; Nagliati, C.; Pennisi, D.; Rizzi, A.; Frattini, F.; Foschi, D.; Benuzzi, L.; Parikh, C.; Shah, H.; Pinotti, E.; Montuori, M.; Borrelli, V.; Dargent, J.; Copaescu, C. A.; Hutopila, I.; Smeu, B.; Witteman, B.; Hazebroek, E.; Deden, L.; Heusschen, L.; Okkema, S.; Aufenacker, T.; den Hengst, W.; Vening, W.; van der Burgh, Y.; Ghazal, A.; Ibrahim, H.; Niazi, M.; Alkhaffaf, B.; Altarawni, M.; Cesana, G. C.; Anselmino, M.; Uccelli, M.; Olmi, S.; Stier, C.; Akmanlar, T.; Sonnenberg, T.; Schieferbein, U.; Marcolini, A.; Awruch, D.; Vicentin, M.; de Souza Bastos, E. L.; Gregorio, S. A.; Ahuja, A.; Mittal, T.; Bolckmans, R.; Wiggins, T.; Baratte, C.; Wisnewsky, J. A.; Genser, L.; Chong, L.; Taylor, L.; Ward, S.; Hi, M. W.; Heneghan, H.; Fearon, N.; Plamper, A.; Rheinwalt, K.; Heneghan, H.; Geoghegan, J.; Ng, K. C.; Fearon, N.; Kaseja, K.; Kotowski, M.; Samarkandy, T. A.; Leyva-Alvizo, A.; Corzo-Culebro, L.; Wang, C.; Yang, W.; Dong, Z.; Riera, M.; Jain, R.; Hamed, H.; Said, M.; Zarzar, K.; Garcia, M.; Turkcapar, A. G.; Sen, O.; Baldini, E.; Conti, L.; Wietzycoski, C.; Lopes, E.; Pintar, T.; Salobir, J.; Aydin, C.; Atici, S. D.; Ergin, A.; Ciyiltepe, H.; Bozkurt, M. A.; Kizilkaya, M. C.; Onalan, N. B. D.; Zuber, M. N. B. A.; Wong, W. J.; Garcia, A.; Vidal, L.; Beisani, M.; Pasquier, J.; Vilallonga, R.; Sharma, S.; Parmar, C.; Lee, L.; Sufi, P.; Sinan, H.; Saydam, M.. - In: INTERNATIONAL JOURNAL OF OBESITY. - ISSN 0307-0565. - 46:4(2021), pp. 750-757-757. [10.1038/s41366-021-01048-1]

30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data

Li A.;Salman M.;Goel R.;Aktas S.;Santonicola A.;Angrisani L.;Iovino P.;Iossa A.;Boru Cristian Eugeniu.;De Angelis F.;Silecchia G.;Tartaglia N.;Torres A.;Torres A.;Kaplan M.;Frattini F.;Shah H.;Montuori M.;Ibrahim H.;Uccelli M.;Marcolini A.;Wang C.;
2021

Abstract

Background: There is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts. Materials and methods: This analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien–Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups. Results: In total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07). Conclusions: This global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1629326
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