The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis.
Comprehensive phenotyping of human peripheral blood b lymphocytes in healthy conditions / Carsetti, R.; Terreri, S.; Conti, M. G.; Fernandez Salinas, A.; Corrente, F.; Capponi, C.; Albano, C.; Piano Mortari, E.. - In: CYTOMETRY. PART A. - ISSN 1552-4922. - 101:2(2022), pp. 131-139. [10.1002/cyto.a.24507]
Comprehensive phenotyping of human peripheral blood b lymphocytes in healthy conditions
Conti M. G.;
2022
Abstract
The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis.| File | Dimensione | Formato | |
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