BACKGROUND: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. It found that perioperative COVID-19 infection was associated with a mortality rate of 24%. At the same time, the COVERstudy demonstrated similarly high perioperative mortality rates in vascular surgical patients undergoing vascular interventions even without COVID-19, likely associated with the high burden of comorbidity associated with vascular patients. This is a vascular subgroup analysis of the COVIDSurg cohort. METHODS: All patients with a suspected or confirmed diagnosis of COVID-19 in the 7 days prior to, or in the 30 days following a vascular procedure were included. The primary outcome was 30-day mortality. Secondary outcomes were pulmonary complications (adult respiratory distress syndrome, pulmonary embolism, pneumonia and respiratory failure). Logistic regression was undertaken for dichotomous outcomes. RESULTS: Overall, 602 patients were included in this subgroup analysis, of which 88.4% were emergencies. The most common operations performed were for vascular-related dialysis access procedures (20.1%, N.=121). The combined 30-day mortality rate was 27.2%. Composite secondary pulmonary outcomes occurred in half of the vascular patients (N.=275, 45.7%). CONCLUSIONS: Mortality following vascular surgery in COVID positive patients was significantly higher than levels reported pre-pandemic, and similar to that seen in other specialties in the COVIDSurg cohort. Initiatives and surgical pathways that ensure vascular patients are protected from exposure to COVID-19 in the peri-operative period are vital to protect against excess mortality.

Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data / Hitchman, L.; Machin, M.; Bruzzaniti, P.; Lapolla, P.; Familiari, P.; Santoro, A.; Picotti, V.; Frati, A.; COVIDSurg Collaborative and Vascular and Endovascular Research, Network. - In: JOURNAL OF CARDIOVASCULAR SURGERY. - ISSN 0021-9509. - 62:6(2021), pp. 558-570. [10.23736/S0021-9509.21.12024-5]

Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data

Bruzzaniti P.;Lapolla P.;Familiari P.;Santoro A.;Picotti V.;Frati A.;
2021

Abstract

BACKGROUND: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. It found that perioperative COVID-19 infection was associated with a mortality rate of 24%. At the same time, the COVERstudy demonstrated similarly high perioperative mortality rates in vascular surgical patients undergoing vascular interventions even without COVID-19, likely associated with the high burden of comorbidity associated with vascular patients. This is a vascular subgroup analysis of the COVIDSurg cohort. METHODS: All patients with a suspected or confirmed diagnosis of COVID-19 in the 7 days prior to, or in the 30 days following a vascular procedure were included. The primary outcome was 30-day mortality. Secondary outcomes were pulmonary complications (adult respiratory distress syndrome, pulmonary embolism, pneumonia and respiratory failure). Logistic regression was undertaken for dichotomous outcomes. RESULTS: Overall, 602 patients were included in this subgroup analysis, of which 88.4% were emergencies. The most common operations performed were for vascular-related dialysis access procedures (20.1%, N.=121). The combined 30-day mortality rate was 27.2%. Composite secondary pulmonary outcomes occurred in half of the vascular patients (N.=275, 45.7%). CONCLUSIONS: Mortality following vascular surgery in COVID positive patients was significantly higher than levels reported pre-pandemic, and similar to that seen in other specialties in the COVIDSurg cohort. Initiatives and surgical pathways that ensure vascular patients are protected from exposure to COVID-19 in the peri-operative period are vital to protect against excess mortality.
COVID-19; health care outcome assessment; vascular surgical procedures; adolescent; adult; aged; aged, 80 and over; child; child, preschool; female; global health; humans; infant; male; middle aged; outcome and process assessment, health care; patient safety; prospective studies; risk assessment; risk factors; time factors; treatment outcome; vascular diseases; vascular surgical procedures; young adult
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Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data / Hitchman, L.; Machin, M.; Bruzzaniti, P.; Lapolla, P.; Familiari, P.; Santoro, A.; Picotti, V.; Frati, A.; COVIDSurg Collaborative and Vascular and Endovascular Research, Network. - In: JOURNAL OF CARDIOVASCULAR SURGERY. - ISSN 0021-9509. - 62:6(2021), pp. 558-570. [10.23736/S0021-9509.21.12024-5]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1629024
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