Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.
Prostatic stromal sarcoma in an adolescent: the role of chemotherapy / Cavaliere, Elena; Alaggio, Rita; Castagnetti, M; Scarzello, G; Bisogno, Gianni. - In: RARE TUMORS. - ISSN 2036-3605. - Volume 6, Issue 4, 23 October 2014, Article number 5607, Pages 146-149:4(2014), pp. 146-149. [10.4081/rt.2014.5607]
Prostatic stromal sarcoma in an adolescent: the role of chemotherapy
ALAGGIO, RITA;
2014
Abstract
Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
