Thin films derived by the deposition of charged microdroplets generated in the ESI source of a mass spectrometer act as highly concentrated reaction vessels in which the final products of an ion−molecule reaction can be isolated by their precipitation onto a solid surface under ambient conditions. In this study, the ESI Z-spray source supplied to a Q-TOF Ultima mass spectrometer was used to investigate the D fructose acid-catalyzed reactions by microdroplets deposition onto a stainless-steel target surface. High conversion ratios of D-fructose into 5-hydroxymethylfuraldehyde (5-HMF), 5-methoxymethylfuraldehyde (5-MMF), and difructrose anhydrides (DFAs) were obtained with HCl and KHSO4 as metal-free catalysts by using synthetic conditions under which the same products in bulk are not formed. Furthermore, the reaction outcome was found to be highly sensitive to the catalyst and the solvent employed as well as to the ESI source parameters influencing the thin film formation from microdroplets deposition onto the solid surface.

Accelerated D‑Fructose acid-catalyzed reactions in thin films formed by charged microdroplets deposition / Salvitti, Chiara; DE PETRIS, Giulia; Troiani, Anna; Manago’, Marta; Villani, Claudio; Ciogli, Alessia; Sorato, Andrea; Ricci, Andreina; Pepi, Federico. - In: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. - ISSN 1879-1123. - 33:3(2022), pp. 565-572. [10.1021/jasms.1c00363]

Accelerated D‑Fructose acid-catalyzed reactions in thin films formed by charged microdroplets deposition

Chiara Salvitti;Giulia de Petris;Anna Troiani;Marta Managò;Claudio Villani;Alessia Ciogli;Andrea Sorato;Federico Pepi
2022

Abstract

Thin films derived by the deposition of charged microdroplets generated in the ESI source of a mass spectrometer act as highly concentrated reaction vessels in which the final products of an ion−molecule reaction can be isolated by their precipitation onto a solid surface under ambient conditions. In this study, the ESI Z-spray source supplied to a Q-TOF Ultima mass spectrometer was used to investigate the D fructose acid-catalyzed reactions by microdroplets deposition onto a stainless-steel target surface. High conversion ratios of D-fructose into 5-hydroxymethylfuraldehyde (5-HMF), 5-methoxymethylfuraldehyde (5-MMF), and difructrose anhydrides (DFAs) were obtained with HCl and KHSO4 as metal-free catalysts by using synthetic conditions under which the same products in bulk are not formed. Furthermore, the reaction outcome was found to be highly sensitive to the catalyst and the solvent employed as well as to the ESI source parameters influencing the thin film formation from microdroplets deposition onto the solid surface.
microdroplets; thin film; D-fructose; dehydration; methylation; dimerization
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Accelerated D‑Fructose acid-catalyzed reactions in thin films formed by charged microdroplets deposition / Salvitti, Chiara; DE PETRIS, Giulia; Troiani, Anna; Manago’, Marta; Villani, Claudio; Ciogli, Alessia; Sorato, Andrea; Ricci, Andreina; Pepi, Federico. - In: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. - ISSN 1879-1123. - 33:3(2022), pp. 565-572. [10.1021/jasms.1c00363]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1623953
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