Distal gastrectomy for benign gastroduodenal peptic disease has become rare, but it still represents a widely adopted procedure for advanced and, in some countries, even for early distal gastric cancer. Survival rates following surgery for gastric malignancy are constantly improving, hence the residual mucosa of the gastric stump is exposed for a prolonged period to biliopancreatic reflux and, possibly, to Helicobacter pylori (HP) infection. Biliopancreatic reflux and HP infection are considered responsible for gastritis and metachronous carcinoma in the gastric stump after oncologic surgery. For gastrectomy patients, in addition to eradication treatment for cases that are already HP positive, endoscopic surveillance should also be recommended, for prompt surveillance and detection in the residual mucosa of any metaplastic-atrophic-dysplastic features following surgery.

Role of new anatomy, biliopancreatic reflux, and helicobacter pylori status in postgastrectomy stump cancer / Basso, Luigi; Gallo, Gaetano; Biacchi, Daniele; Carati, Maria Vittoria; Cavallaro, Giuseppe; Esposito, Luca; Giuliani, Andrea; Izzo, Luciano; Izzo, Paolo; Lamazza, Antonietta; Polistena, Andrea; Tarallo, Mariarita; Micarelli, Alessandro; Fiori, Enrico. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 11:6(2022), p. 1498. [10.3390/jcm11061498]

Role of new anatomy, biliopancreatic reflux, and helicobacter pylori status in postgastrectomy stump cancer

Basso, Luigi
Primo
;
Gallo, Gaetano;Biacchi, Daniele;Carati, Maria Vittoria;Cavallaro, Giuseppe;Esposito, Luca;Giuliani, Andrea;Izzo, Luciano;Lamazza, Antonietta;Polistena, Andrea;Tarallo, Mariarita;Fiori, Enrico
Ultimo
;
GALLO, Gaetano
2022

Abstract

Distal gastrectomy for benign gastroduodenal peptic disease has become rare, but it still represents a widely adopted procedure for advanced and, in some countries, even for early distal gastric cancer. Survival rates following surgery for gastric malignancy are constantly improving, hence the residual mucosa of the gastric stump is exposed for a prolonged period to biliopancreatic reflux and, possibly, to Helicobacter pylori (HP) infection. Biliopancreatic reflux and HP infection are considered responsible for gastritis and metachronous carcinoma in the gastric stump after oncologic surgery. For gastrectomy patients, in addition to eradication treatment for cases that are already HP positive, endoscopic surveillance should also be recommended, for prompt surveillance and detection in the residual mucosa of any metaplastic-atrophic-dysplastic features following surgery.
2022
Gastric cancer; biliopancreatic reflux; gastritis; carcinoma; endoscopic surveillance; Helicobacter pylori infection; gastric stump cancer
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Role of new anatomy, biliopancreatic reflux, and helicobacter pylori status in postgastrectomy stump cancer / Basso, Luigi; Gallo, Gaetano; Biacchi, Daniele; Carati, Maria Vittoria; Cavallaro, Giuseppe; Esposito, Luca; Giuliani, Andrea; Izzo, Luciano; Izzo, Paolo; Lamazza, Antonietta; Polistena, Andrea; Tarallo, Mariarita; Micarelli, Alessandro; Fiori, Enrico. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 11:6(2022), p. 1498. [10.3390/jcm11061498]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1619948
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