Ph-like acute lymphoblastic leukemia (BCR/ABL1-like ALL) is a subset of B-lineage ALL with a gene expression profile (GEP) similar to that of BCR/ABL1-positive (BCR/ABL1þ) ALL, but lacking the BCR-ABL1 fusion protein derived from the t(9;22)(q34;q11) translocation. It is unknown whether BCR/ABL1-like ALL cases are associated with distinctive morphologic features of the leukemic cells.
Blast morphology in the diagnostic work-up of Ph-like acute lymphoblastic leukemia / Fazio, F.; Cunsolo, G.; Mancini, F.; Piciocchi, A.; Arena, V.; Messina, M.; Ansuinelli, M.; Taherinasab, A.; Apicella, V.; Vitale, A.; Chiaretti, S.; Guarini, A.; Del Giudice, I.; Foà, R.. - In: LEUKEMIA & LYMPHOMA. - ISSN 1042-8194. - (2022), pp. 1-3.
Blast morphology in the diagnostic work-up of Ph-like acute lymphoblastic leukemia
F. Fazio
;G. Cunsolo;F. Mancini;A. Piciocchi;V. Arena;M. Messina;M. Ansuinelli;A. Taherinasab;S. Chiaretti;A. Guarini;I. Del Giudice;R. Foà
2022
Abstract
Ph-like acute lymphoblastic leukemia (BCR/ABL1-like ALL) is a subset of B-lineage ALL with a gene expression profile (GEP) similar to that of BCR/ABL1-positive (BCR/ABL1þ) ALL, but lacking the BCR-ABL1 fusion protein derived from the t(9;22)(q34;q11) translocation. It is unknown whether BCR/ABL1-like ALL cases are associated with distinctive morphologic features of the leukemic cells.| File | Dimensione | Formato | |
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