OBJECTIVE: In Parkinson’s disease (PD), postural abnormalities such as lateral axial dystonia (LAD) are relatively common. Evidence suggests that both peripheral and central mechanisms contribute to these postural abnormalities. We previously reported an improvement in LAD following the use of prisms in two PD patients. Here, we further investigate the effects of prismatic lenses in a case series of nine patients with PD and LAD. METHODS: Nine patients underwent an orthoptic evaluation and were provided with prismatic lenses. Patients were evaluated at baseline and after one and three months of permanent prismatic lens use and again re-evaluated one month after the discontinuation of prismatic lens use. RESULTS: We found a linear relationship between disease duration and LAD severity. Compared to basal measurements, we observed a slight improvement in LAD. Furthermore, we found a significant reduction in self-perceived back pain due to the use of prismatic lenses. There was no significant association between the individual effects of prismatic lenses in patients with PD and their baseline LAD or other clinical and demographic features (all P>0.05). CONCLUSION: The present pilot study provides novel data on the possible effectiveness of prismatic lenses for LAD treatment in PD patients.

Effects of prismatic lenses on lateral axial dystonia in parkinson's disease: A pilot study / Meglio, M.; Olivola, E.; Santilli, M.; Lena, F.; Centonze, D.; Bologna, M.; Modugno, N.. - In: INNOVATIONS IN CLINICAL NEUROSCIENCE. - ISSN 2158-8333. - 18:1-3(2021), pp. 39-42.

Effects of prismatic lenses on lateral axial dystonia in parkinson's disease: A pilot study

Lena F.;Bologna M.;Modugno N.
2021

Abstract

OBJECTIVE: In Parkinson’s disease (PD), postural abnormalities such as lateral axial dystonia (LAD) are relatively common. Evidence suggests that both peripheral and central mechanisms contribute to these postural abnormalities. We previously reported an improvement in LAD following the use of prisms in two PD patients. Here, we further investigate the effects of prismatic lenses in a case series of nine patients with PD and LAD. METHODS: Nine patients underwent an orthoptic evaluation and were provided with prismatic lenses. Patients were evaluated at baseline and after one and three months of permanent prismatic lens use and again re-evaluated one month after the discontinuation of prismatic lens use. RESULTS: We found a linear relationship between disease duration and LAD severity. Compared to basal measurements, we observed a slight improvement in LAD. Furthermore, we found a significant reduction in self-perceived back pain due to the use of prismatic lenses. There was no significant association between the individual effects of prismatic lenses in patients with PD and their baseline LAD or other clinical and demographic features (all P>0.05). CONCLUSION: The present pilot study provides novel data on the possible effectiveness of prismatic lenses for LAD treatment in PD patients.
2021
Lateral axial dystonia; Oculo-motor system; Parkinson's disease (PD); Pisa syndrome; Prisms
01 Pubblicazione su rivista::01a Articolo in rivista
Effects of prismatic lenses on lateral axial dystonia in parkinson's disease: A pilot study / Meglio, M.; Olivola, E.; Santilli, M.; Lena, F.; Centonze, D.; Bologna, M.; Modugno, N.. - In: INNOVATIONS IN CLINICAL NEUROSCIENCE. - ISSN 2158-8333. - 18:1-3(2021), pp. 39-42.
File allegati a questo prodotto
File Dimensione Formato  
effect meglio lena.pdf

solo gestori archivio

Note: Meglio_Effects of Prismatic Lenses_2021
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 85.13 kB
Formato Adobe PDF
85.13 kB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1610475
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? ND
social impact