The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane. ERp57/PDIA3 is an important research target considering it can be found in various subcellular locations. This protein is involved in many different physiological and pathological processes, and our review describes new data on its functions and summarizes some ligands identified as PDIA3-specific inhibitors.

ERp57/PDIA3: new insight / Chichiarelli, Silvia; Altieri, Fabio; Paglia, Giuliano; Rubini, Elisabetta; Minacori, Marco; Eufemi, Margherita. - In: CELLULAR & MOLECULAR BIOLOGY LETTERS. - ISSN 1425-8153. - 27:1(2022), p. 12. [10.1186/s11658-022-00315-x]

ERp57/PDIA3: new insight

Chichiarelli, Silvia
;
Altieri, Fabio;Paglia, Giuliano;Rubini, Elisabetta;Minacori, Marco;Eufemi, Margherita
2022

Abstract

The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane. ERp57/PDIA3 is an important research target considering it can be found in various subcellular locations. This protein is involved in many different physiological and pathological processes, and our review describes new data on its functions and summarizes some ligands identified as PDIA3-specific inhibitors.
2022
ERp57; PDIA3; PDI inhibitors; punicalagin; vitamin D3; cancer; nervous system; fertility; infections; cardiovascular system
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
ERp57/PDIA3: new insight / Chichiarelli, Silvia; Altieri, Fabio; Paglia, Giuliano; Rubini, Elisabetta; Minacori, Marco; Eufemi, Margherita. - In: CELLULAR & MOLECULAR BIOLOGY LETTERS. - ISSN 1425-8153. - 27:1(2022), p. 12. [10.1186/s11658-022-00315-x]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1609489
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