Camps et al. describe a cell population that blocks fat turnover in the skeletal muscle by single-cell analysis. Furthermore, they show that this population acts through GDF10 secretion and is reduced in dystrophic muscle. This could be an essential turning point in the progressive deterioration of muscular dystrophy patients.
Interstitial cell remodeling promotes aberrant adipogenesis in dystrophic muscles / Camps, J.; Breuls, N.; Sifrim, A.; Giarratana, N.; Corvelyn, M.; Danti, L.; Grosemans, H.; Vanuytven, S.; Thiry, I.; Belicchi, M.; Meregalli, M.; Platko, K.; MacDonald, M. E.; Austin, R. C.; Gijsbers, R.; Cossu, G.; Torrente, Y.; Voet, T.; Sampaolesi, M.. - In: CELL REPORTS. - ISSN 2211-1247. - 31:5(2020), pp. 1-21. [10.1016/j.celrep.2020.107597]
Interstitial cell remodeling promotes aberrant adipogenesis in dystrophic muscles
Sampaolesi M.
2020
Abstract
Camps et al. describe a cell population that blocks fat turnover in the skeletal muscle by single-cell analysis. Furthermore, they show that this population acts through GDF10 secretion and is reduced in dystrophic muscle. This could be an essential turning point in the progressive deterioration of muscular dystrophy patients.| File | Dimensione | Formato | |
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Camps_Interstitial_2020.pdf
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