Purpose: Prostatic tissue in an ovarian teratoma is an unusual finding, whose initiation in a 46, XX karyotype tissue is yet to be clarified. We present a case from our files and review the literature for this intriguing finding. Methods: Unstained histology sections of the ovarian teratoma containing prostatic tissue were evaluated using immunohistochemistry for PSA and androgen receptor. Results: Both PSA and androgen receptor immunostainings were positive in the prostatic tissue. From the literature review, it appears that most of the patients (74%) with similar findings were either pregnant or experiencing a miscarriage, menopausal or infertile at presentation, showing that an imbalanced hormone status is frequently associated with the presence of male structures in ovarian teratomas.
Prostatic tissue: an unexpected finding in a mature ovarian teratoma: case report and systematic literature review / Pecorella, Irene; Framarino Dei Malatesta, Maria Luisa; Riganelli, Lucia; Ciardi, Gaia; Porpora, Maria Grazia. - In: ARCHIVES OF GYNECOLOGY AND OBSTETRICS. - ISSN 0932-0067. - 4(2022), pp. 969-976. [10.1007/s00404-021-06245-x]
Prostatic tissue: an unexpected finding in a mature ovarian teratoma: case report and systematic literature review
Pecorella, Irene
Primo
;Framarino Dei Malatesta, Maria LuisaSecondo
;Riganelli, Lucia;Porpora, Maria GraziaUltimo
2022
Abstract
Purpose: Prostatic tissue in an ovarian teratoma is an unusual finding, whose initiation in a 46, XX karyotype tissue is yet to be clarified. We present a case from our files and review the literature for this intriguing finding. Methods: Unstained histology sections of the ovarian teratoma containing prostatic tissue were evaluated using immunohistochemistry for PSA and androgen receptor. Results: Both PSA and androgen receptor immunostainings were positive in the prostatic tissue. From the literature review, it appears that most of the patients (74%) with similar findings were either pregnant or experiencing a miscarriage, menopausal or infertile at presentation, showing that an imbalanced hormone status is frequently associated with the presence of male structures in ovarian teratomas.File | Dimensione | Formato | |
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Pecorella_Prostatic Tissue_2021.pdf
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Note: https://link.springer.com/article/10.1007/s00404-021-06245-x
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