Purpose: Prostatic tissue in an ovarian teratoma is an unusual finding, whose initiation in a 46, XX karyotype tissue is yet to be clarified. We present a case from our files and review the literature for this intriguing finding. Methods: Unstained histology sections of the ovarian teratoma containing prostatic tissue were evaluated using immunohistochemistry for PSA and androgen receptor. Results: Both PSA and androgen receptor immunostainings were positive in the prostatic tissue. From the literature review, it appears that most of the patients (74%) with similar findings were either pregnant or experiencing a miscarriage, menopausal or infertile at presentation, showing that an imbalanced hormone status is frequently associated with the presence of male structures in ovarian teratomas.

Prostatic tissue: an unexpected finding in a mature ovarian teratoma: case report and systematic literature review / Pecorella, Irene; Framarino Dei Malatesta, Maria Luisa; Riganelli, Lucia; Ciardi, Gaia; Porpora, Maria Grazia. - In: ARCHIVES OF GYNECOLOGY AND OBSTETRICS. - ISSN 0932-0067. - 4(2022), pp. 969-976. [10.1007/s00404-021-06245-x]

Prostatic tissue: an unexpected finding in a mature ovarian teratoma: case report and systematic literature review

Pecorella, Irene
Primo
;
Framarino Dei Malatesta, Maria Luisa
Secondo
;
Riganelli, Lucia;Porpora, Maria Grazia
Ultimo
2022

Abstract

Purpose: Prostatic tissue in an ovarian teratoma is an unusual finding, whose initiation in a 46, XX karyotype tissue is yet to be clarified. We present a case from our files and review the literature for this intriguing finding. Methods: Unstained histology sections of the ovarian teratoma containing prostatic tissue were evaluated using immunohistochemistry for PSA and androgen receptor. Results: Both PSA and androgen receptor immunostainings were positive in the prostatic tissue. From the literature review, it appears that most of the patients (74%) with similar findings were either pregnant or experiencing a miscarriage, menopausal or infertile at presentation, showing that an imbalanced hormone status is frequently associated with the presence of male structures in ovarian teratomas.
2022
AR; heterotopic tissue; immunohistochemistry; ovarian teratoma; PSA; prostatic tissue
01 Pubblicazione su rivista::01a Articolo in rivista
Prostatic tissue: an unexpected finding in a mature ovarian teratoma: case report and systematic literature review / Pecorella, Irene; Framarino Dei Malatesta, Maria Luisa; Riganelli, Lucia; Ciardi, Gaia; Porpora, Maria Grazia. - In: ARCHIVES OF GYNECOLOGY AND OBSTETRICS. - ISSN 0932-0067. - 4(2022), pp. 969-976. [10.1007/s00404-021-06245-x]
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Note: https://link.springer.com/article/10.1007/s00404-021-06245-x
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1576869
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