Previous investigations have shown that the extent of myocardial hypertrophy and fibrosis,1,2 as well as the degree of haemodynamic derangement in hypertrophic cardiomyopathy (HCM) are connected to the activation of measures of myocardial inflammation,1 including nuclear factor-kappa B (NF-kB) which is a transcription factor regulating expression of genes that play a major role in inflammation, cell growth, and apoptosis.
Nuclear factor-kappa B predicts long-term clinical outcome in patients with hypertrophic cardiomyopathy. 10-year follow-up study / Pelliccia, Francesco; Limongelli, Giuseppe; Rosano, Giuseppe M C; Vitale, Cristiana; Bossone, Eduardo; Calabrò, Paolo; Gaudio, Carlo. - In: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. - ISSN 2047-4873. - 29:3(2022), pp. E8-E11. [10.1093/eurjpc/zwab047]
Nuclear factor-kappa B predicts long-term clinical outcome in patients with hypertrophic cardiomyopathy. 10-year follow-up study
Pelliccia, Francesco
Primo
;Gaudio, Carlo
2022
Abstract
Previous investigations have shown that the extent of myocardial hypertrophy and fibrosis,1,2 as well as the degree of haemodynamic derangement in hypertrophic cardiomyopathy (HCM) are connected to the activation of measures of myocardial inflammation,1 including nuclear factor-kappa B (NF-kB) which is a transcription factor regulating expression of genes that play a major role in inflammation, cell growth, and apoptosis.| File | Dimensione | Formato | |
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