Well-defined germ-line mutations in the PTCH1 gene are associated with syndromic multiple basal cell carcinomas (BCCs). Here, we used whole exome sequencing (WES) to identify the role of patched-1 in patients with multiple, unusually large BCCs.
Genetic Predisposition to Numerous Large Ulcerating Basal Cell Carcinomas and Response to Immune Therapy / Dasgeb, Bahar; Leila, Youssefian; Saeidian, Amir Hossein; Kang, Jun; Shi, Wenyin; Shoenberg, Elizabeth; Ertel, Adam; Fortina, Paolo; Vahidnezhad, Hassan; Uitto, Jouni. - In: INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY. - ISSN 2641-8746. - 4:2(2021), pp. 70-75. [10.1097/JD9.0000000000000170]
Genetic Predisposition to Numerous Large Ulcerating Basal Cell Carcinomas and Response to Immune Therapy
Fortina, PaoloMembro del Collaboration Group
;
2021
Abstract
Well-defined germ-line mutations in the PTCH1 gene are associated with syndromic multiple basal cell carcinomas (BCCs). Here, we used whole exome sequencing (WES) to identify the role of patched-1 in patients with multiple, unusually large BCCs.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
