AstroBio CubeSat (ABCS) is a 3U CubeSat that will operate within the internal Van Allen belt and it should be the first attempt to conduct biochemical experiments on a nanosatellite platform and in a so extremely harsh environment. Performing astrobiology research in space is surely challenging due to limited volumes, limited access, and stressors such as ionizing radiation and lack of convection. Moreover, experiments should be performed autonomously especially on CubeSat missions. This interdisciplinary field requires also a comprehensive, integrated understanding of biological, biochemical and planetary phenomena. To meet the requirements arising from this scenario, ABCS satellite integrates several innovative solutions ranging from optimized experimental protocol to peculiar system level arrangements. The core of ABCS payload will be a lab-on-chip device consisting of a glass substrate on which a series of lateral flow immuno-assay (LFIA) strips on nitrocellulose support are attached. LFIA strips will be functionalized with biomolecules, immobilized in specific test areas, that will be sensed by means of chemiluminescent (CL) reactions. To avoid degradation of assay chemicals these will be deposited in a non-permanent fashion in a dry form in the initial part of the strips. On-chip detection of the analytical chemiluminescent signal, that occurs at test areas, is performed by means of hydrogenated amorphous silicon photodiodes. A custom low noise front-end readout board is employed for the biasing of the photodiode array and the readout of the photocurrents signal that contains the analytical information. In addition, it allows to interface the chip with the on-board computer. To carry out experiments in a stand-alone fashion, a third electronic board, stacked over the former, hosts a set of micropumps for the delivery of reagents across the device. Payload operation requires an ambient-pressure environment which is ensured by an aluminium box, hermetically sealed with an indium wire gasket. The box also provides shielding capability from the environment ionizing radiation. In this work an over-view of the engineering solutions employed to meet the requirements of a CubeSat application is presented.

Astrobio cubesat: Enabling technologies for astrobiology research in space / Iannascoli, Lorenzo; Nascetti, Augusto; Carletta, Stefano; Schirone, Luigi; Meneghin, Andrea; Robert Brucato, John; Paglialunga, Daniele; Poggiali, Giovanni; Pirrotta, Simone; Impresario, Gabriele; Sabatini, Alessia; Pacelli, Claudia. - 2020:(2020), pp. 1-5. ((Intervento presentato al convegno 71st International Astronautical Congress, IAC 2020 tenutosi a Virtual Event.

Astrobio cubesat: Enabling technologies for astrobiology research in space

Lorenzo Iannascoli
;
Augusto Nascetti;Stefano Carletta;Luigi Schirone;Daniele Paglialunga;
2020

Abstract

AstroBio CubeSat (ABCS) is a 3U CubeSat that will operate within the internal Van Allen belt and it should be the first attempt to conduct biochemical experiments on a nanosatellite platform and in a so extremely harsh environment. Performing astrobiology research in space is surely challenging due to limited volumes, limited access, and stressors such as ionizing radiation and lack of convection. Moreover, experiments should be performed autonomously especially on CubeSat missions. This interdisciplinary field requires also a comprehensive, integrated understanding of biological, biochemical and planetary phenomena. To meet the requirements arising from this scenario, ABCS satellite integrates several innovative solutions ranging from optimized experimental protocol to peculiar system level arrangements. The core of ABCS payload will be a lab-on-chip device consisting of a glass substrate on which a series of lateral flow immuno-assay (LFIA) strips on nitrocellulose support are attached. LFIA strips will be functionalized with biomolecules, immobilized in specific test areas, that will be sensed by means of chemiluminescent (CL) reactions. To avoid degradation of assay chemicals these will be deposited in a non-permanent fashion in a dry form in the initial part of the strips. On-chip detection of the analytical chemiluminescent signal, that occurs at test areas, is performed by means of hydrogenated amorphous silicon photodiodes. A custom low noise front-end readout board is employed for the biasing of the photodiode array and the readout of the photocurrents signal that contains the analytical information. In addition, it allows to interface the chip with the on-board computer. To carry out experiments in a stand-alone fashion, a third electronic board, stacked over the former, hosts a set of micropumps for the delivery of reagents across the device. Payload operation requires an ambient-pressure environment which is ensured by an aluminium box, hermetically sealed with an indium wire gasket. The box also provides shielding capability from the environment ionizing radiation. In this work an over-view of the engineering solutions employed to meet the requirements of a CubeSat application is presented.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1574059
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