Covid19 mostly manifests with interstitial pneumonia, even though it can afect heart and central nervous system as well. Although the pathophysiology of the clinical manifestations of Covid19 is not yet completely known, it has been shown that the entry of Sars-CoV-2 into cells is mediated by angiotensin-converting enzyme 2 (ACE2), expressed also in pulmonary epithelium [2]. After that, symptoms and the severity of Covid19 depend on the virus replication but also on the individual's immune response, often establishing an immune/infammatory storm leading to tissue damage that can have severe prognosis

Repurposing cardio-metabolic drugs to fight Covid19 / Battistoni, A.; Volpe, M.. - In: HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION. - ISSN 1120-9879. - 28:5(2021), pp. 419-423. [10.1007/s40292-021-00475-5]

Repurposing cardio-metabolic drugs to fight Covid19

Battistoni A.;Volpe M.
2021

Abstract

Covid19 mostly manifests with interstitial pneumonia, even though it can afect heart and central nervous system as well. Although the pathophysiology of the clinical manifestations of Covid19 is not yet completely known, it has been shown that the entry of Sars-CoV-2 into cells is mediated by angiotensin-converting enzyme 2 (ACE2), expressed also in pulmonary epithelium [2]. After that, symptoms and the severity of Covid19 depend on the virus replication but also on the individual's immune response, often establishing an immune/infammatory storm leading to tissue damage that can have severe prognosis
File allegati a questo prodotto
File Dimensione Formato  
Battistoni_Repurposing_2021.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 431.16 kB
Formato Adobe PDF
431.16 kB Adobe PDF Visualizza/Apri PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1574023
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact