Schistocytes are fragments of red blood cells which maybe encountered in the peripheral blood smear of patientssufering from a variety of microangiopathic diseases. In the hospitalized COVID-19 patients at diferent stages of disease severity, a schistocyte count ≥ 1% was documented in approximately 70% of patients. Evidence of myocardial injury was observed in 87.5% of all who had a count of schistocytes ≥ 1%. Schistocytes may serve as a simple and inexpensive biomarker to identify a high-risk subpopulation with a latent systemic microvascular damage irrespective of respiratory symptoms
Evidence of systemic endothelial injury and microthrombosis in hospitalized COVID-19 patients at different stages of the disease / Della Rocca, D.G., Magnocavallo, M., Lavalle, C., Romero, J., Forleo, G.B., Tarantino, N., Chimenti, C., Alviz, I., Gamero, M.T., Garcia, M.J., Di Biase, L., Natale, A.. - In: JOURNAL OF THROMBOSIS AND THROMBOLYSIS. - ISSN 0929-5305. - 51:3(2021), pp. 571-576. [10.1007/s11239-020-02330-1]
Evidence of systemic endothelial injury and microthrombosis in hospitalized COVID-19 patients at different stages of the disease
Magnocavallo M.
Co-primo
;Lavalle C.;Chimenti C.;
2021
Abstract
Schistocytes are fragments of red blood cells which maybe encountered in the peripheral blood smear of patientssufering from a variety of microangiopathic diseases. In the hospitalized COVID-19 patients at diferent stages of disease severity, a schistocyte count ≥ 1% was documented in approximately 70% of patients. Evidence of myocardial injury was observed in 87.5% of all who had a count of schistocytes ≥ 1%. Schistocytes may serve as a simple and inexpensive biomarker to identify a high-risk subpopulation with a latent systemic microvascular damage irrespective of respiratory symptoms| File | Dimensione | Formato | |
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