Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the hair follicle. Albeit, its pathogenesis, is multifactorial; HS is regarded as mainly auto-inflammatory in its origin.1 In partic- ular, the high expression levels of interleukin (IL)-17A in the bloodstream2 and in lesional skin3,4 of patients with HS, allow us to consider secukinumab as a potential drug capable of arrest- ing the inflammatory cascade that characterizes this complicated pathology. We carried out a multicentric retrospective study collecting 31 patients.
Effectiveness of Secukinumab in the treatment of moderate–severe hidradenitis suppurativa. Results from an Italian multicentric retrospective study in a real-life setting / Ribero, S; Ramondetta, A; Fabbrocini, G; Bettoli, V; Potenza, C; Chiricozzi, A; Licciardello, M; Marzano, Av; Bianchi, L; Rozzo, G; Fania, L; Marasca, C; Odorici, G; Mambrin, A; Moltrasio, C; Caposiena Caro, Rd; Skroza, N; Quaglino, P; Siliquini, N; Dapavo, P. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 0926-9959. - 35:7(2021), pp. 441-442. [10.1111/jdv.17178]
Effectiveness of Secukinumab in the treatment of moderate–severe hidradenitis suppurativa. Results from an Italian multicentric retrospective study in a real-life setting
Potenza C;Mambrin A;Skroza N;
2021
Abstract
Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the hair follicle. Albeit, its pathogenesis, is multifactorial; HS is regarded as mainly auto-inflammatory in its origin.1 In partic- ular, the high expression levels of interleukin (IL)-17A in the bloodstream2 and in lesional skin3,4 of patients with HS, allow us to consider secukinumab as a potential drug capable of arrest- ing the inflammatory cascade that characterizes this complicated pathology. We carried out a multicentric retrospective study collecting 31 patients.File | Dimensione | Formato | |
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Ribero_Effectiveness-Secukinumab_2021.pdf
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Note: https://onlinelibrary.wiley.com/doi/10.1111/jdv.17178
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