The FLASH Radiotherapy is a revolutionary new tech-nique in the cancer cure: it spares healthy tissue from thedamage of the ionizing radiation maintaining the tumor con-trol as efficient as in the conventional radiotherapy. To allowthe implementation of the FLASH Therapy concept intoactual clinical use, it is necessary to have an acceleratorable to deliver high dose per pulse (>1-2 Gy) in very shorttime pulse duration (s) and high dose rate (>106Gy/s).Today, low energy (up to 7 MeV) S-band LINACs are beingused in radiobiology and pre-clinical applications. However,in order to treat deep tumors the energy of the electronsshould achieve the range of 50-250 MeV [1] [2]. In thispaper we address the main issues in the design of a compactC band (5.712 GHz) Very High Electron Energy (VHEE)for FLASH Radiotherapy. We present preliminary studiesof a C-band system done at La Sapienza and INFN, aimingto reach a high accelerating gradient and high current neces-sary to deliver a dose>1 Gy/pulse, within a beam pulse ofs.

Preliminary Studies of a Compact VHEE Linear Accelerator System for FLASH Radiotherapy / Giuliano, Lucia; Alesini, David; Behtouei, Mostafa; Bosco, Fabio; Carillo, Martina; Cuttone, Giacomo; DE ARCANGELIS, Daniele; Faillace, Luigi; Favaudon, Vincent; Ficcadenti, Luca; Heinrich, Sophie; Migliorati, Mauro; Mostacci, Andrea; Palumbo, Luigi; Patriarca, Annalisa; Spataro, Bruno; Torrisi, Giuseppe. - (2021), pp. 1229-1232. ((Intervento presentato al convegno 12th Int. Particle Acc. Conf. IPAC2021 tenutosi a Campinas, SP, Brazil [10.18429/jacow-ipac2021-mopab410].

Preliminary Studies of a Compact VHEE Linear Accelerator System for FLASH Radiotherapy

Lucia Giuliano
Primo
Writing – Original Draft Preparation
;
David Alesini
Membro del Collaboration Group
;
Mostafa Behtouei
Membro del Collaboration Group
;
Fabio Bosco
Membro del Collaboration Group
;
Martina Carillo
Membro del Collaboration Group
;
Daniele De Arcangelis
Membro del Collaboration Group
;
Luigi Faillace
Ultimo
Membro del Collaboration Group
;
Luca Ficcadenti
Membro del Collaboration Group
;
Mauro Migliorati
Membro del Collaboration Group
;
Andrea Mostacci
Membro del Collaboration Group
;
Luigi Palumbo
Penultimo
Supervision
;
Annalisa Patriarca
Membro del Collaboration Group
;
Bruno Spataro
Membro del Collaboration Group
;
Giuseppe Torrisi
Membro del Collaboration Group
2021

Abstract

The FLASH Radiotherapy is a revolutionary new tech-nique in the cancer cure: it spares healthy tissue from thedamage of the ionizing radiation maintaining the tumor con-trol as efficient as in the conventional radiotherapy. To allowthe implementation of the FLASH Therapy concept intoactual clinical use, it is necessary to have an acceleratorable to deliver high dose per pulse (>1-2 Gy) in very shorttime pulse duration (s) and high dose rate (>106Gy/s).Today, low energy (up to 7 MeV) S-band LINACs are beingused in radiobiology and pre-clinical applications. However,in order to treat deep tumors the energy of the electronsshould achieve the range of 50-250 MeV [1] [2]. In thispaper we address the main issues in the design of a compactC band (5.712 GHz) Very High Electron Energy (VHEE)for FLASH Radiotherapy. We present preliminary studiesof a C-band system done at La Sapienza and INFN, aimingto reach a high accelerating gradient and high current neces-sary to deliver a dose>1 Gy/pulse, within a beam pulse ofs.
12th Int. Particle Acc. Conf. IPAC2021
Flash therapy, medical linac, high dose rate, VHEE
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
Preliminary Studies of a Compact VHEE Linear Accelerator System for FLASH Radiotherapy / Giuliano, Lucia; Alesini, David; Behtouei, Mostafa; Bosco, Fabio; Carillo, Martina; Cuttone, Giacomo; DE ARCANGELIS, Daniele; Faillace, Luigi; Favaudon, Vincent; Ficcadenti, Luca; Heinrich, Sophie; Migliorati, Mauro; Mostacci, Andrea; Palumbo, Luigi; Patriarca, Annalisa; Spataro, Bruno; Torrisi, Giuseppe. - (2021), pp. 1229-1232. ((Intervento presentato al convegno 12th Int. Particle Acc. Conf. IPAC2021 tenutosi a Campinas, SP, Brazil [10.18429/jacow-ipac2021-mopab410].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1571261
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