The FLASH Radiotherapy is a revolutionary new tech-nique in the cancer cure: it spares healthy tissue from thedamage of the ionizing radiation maintaining the tumor con-trol as efficient as in the conventional radiotherapy. To allowthe implementation of the FLASH Therapy concept intoactual clinical use, it is necessary to have an acceleratorable to deliver high dose per pulse (>1-2 Gy) in very shorttime pulse duration (s) and high dose rate (>106Gy/s).Today, low energy (up to 7 MeV) S-band LINACs are beingused in radiobiology and pre-clinical applications. However,in order to treat deep tumors the energy of the electronsshould achieve the range of 50-250 MeV [1] [2]. In thispaper we address the main issues in the design of a compactC band (5.712 GHz) Very High Electron Energy (VHEE)for FLASH Radiotherapy. We present preliminary studiesof a C-band system done at La Sapienza and INFN, aimingto reach a high accelerating gradient and high current neces-sary to deliver a dose>1 Gy/pulse, within a beam pulse ofs.
Preliminary Studies of a Compact VHEE Linear Accelerator System for FLASH Radiotherapy / Giuliano, Lucia; Alesini, David; Behtouei, Mostafa; Bosco, Fabio; Carillo, Martina; Cuttone, Giacomo; DE ARCANGELIS, Daniele; Faillace, Luigi; Favaudon, Vincent; Ficcadenti, Luca; Heinrich, Sophie; Migliorati, Mauro; Mostacci, Andrea; Palumbo, Luigi; Patriarca, Annalisa; Spataro, Bruno; Torrisi, Giuseppe. - (2021), pp. 1229-1232. (Intervento presentato al convegno 12th Int. Particle Acc. Conf. IPAC2021 tenutosi a Campinas, SP, Brazil) [10.18429/jacow-ipac2021-mopab410].
Preliminary Studies of a Compact VHEE Linear Accelerator System for FLASH Radiotherapy
Lucia Giuliano
Primo
Writing – Original Draft Preparation
;David AlesiniMembro del Collaboration Group
;Mostafa BehtoueiMembro del Collaboration Group
;Fabio BoscoMembro del Collaboration Group
;Martina CarilloMembro del Collaboration Group
;Daniele De ArcangelisMembro del Collaboration Group
;Luigi FaillaceUltimo
Membro del Collaboration Group
;Luca FiccadentiMembro del Collaboration Group
;Mauro MiglioratiMembro del Collaboration Group
;Andrea MostacciMembro del Collaboration Group
;Luigi PalumboPenultimo
Supervision
;Annalisa PatriarcaMembro del Collaboration Group
;Bruno SpataroMembro del Collaboration Group
;Giuseppe TorrisiMembro del Collaboration Group
2021
Abstract
The FLASH Radiotherapy is a revolutionary new tech-nique in the cancer cure: it spares healthy tissue from thedamage of the ionizing radiation maintaining the tumor con-trol as efficient as in the conventional radiotherapy. To allowthe implementation of the FLASH Therapy concept intoactual clinical use, it is necessary to have an acceleratorable to deliver high dose per pulse (>1-2 Gy) in very shorttime pulse duration (s) and high dose rate (>106Gy/s).Today, low energy (up to 7 MeV) S-band LINACs are beingused in radiobiology and pre-clinical applications. However,in order to treat deep tumors the energy of the electronsshould achieve the range of 50-250 MeV [1] [2]. In thispaper we address the main issues in the design of a compactC band (5.712 GHz) Very High Electron Energy (VHEE)for FLASH Radiotherapy. We present preliminary studiesof a C-band system done at La Sapienza and INFN, aimingto reach a high accelerating gradient and high current neces-sary to deliver a dose>1 Gy/pulse, within a beam pulse ofs.File | Dimensione | Formato | |
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