Although discrimination of the model for end stage liver disease (MELD) is generally considered acceptable, its calibration is still unclear. In a validation study, we assessed the discrimination and calibration performance of 3 versions of the model: original MELD-TIPS, used to predict survival after transjugular intra-hepatic portosystemic shunt (TIPS); classic MELD-Mayo; MELD-UNOS, used by United Network for Organ Sharing (UNOS). Recalibration and model updating were also explored.
Performance of the model for end-stage liver disease score for mortality prediction and the potential role of etiology / D'Amico, Gennaro; Maruzzelli, Luigi; Airoldi, Aldo; Petridis, Ioannis; Tosetti, Giulia; Rampoldi, Antonio; D'Amico, Mario; Miraglia, Roberto; De Nicola, Stella; La Mura, Vincenzo; Solcia, Marco; Volpes, Riccardo; Perricone, Giovanni; Sgrazzutti, Cristiano; Vanzulli, Angelo; Primignani, Massimo; Luca, Angelo; Malizia, Giuseppe; Federico, Alessandro; Dallio, Marcello; Andriulli, Angelo; Iacobellis, Angelo; Addario, Luigi; Garcovich, Matteo; Gasbarrini, Antonio; Chessa, Luchino; Salerno, Francesco; Gobbo, Giulia; Merli, Manuela; Ridola, Lorenzo; Baroni, Gianluca Svegliati; Tarantino, Giuseppe; Caporaso, Nicola; Morisco, Filomena; Pozzoni, Pietro; Colli, Agostino; Belli, Luca Saverio. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 75:6(2021), pp. 1355-1366. [10.1016/j.jhep.2021.07.018]
Performance of the model for end-stage liver disease score for mortality prediction and the potential role of etiology
Merli, Manuela;Ridola, Lorenzo;
2021
Abstract
Although discrimination of the model for end stage liver disease (MELD) is generally considered acceptable, its calibration is still unclear. In a validation study, we assessed the discrimination and calibration performance of 3 versions of the model: original MELD-TIPS, used to predict survival after transjugular intra-hepatic portosystemic shunt (TIPS); classic MELD-Mayo; MELD-UNOS, used by United Network for Organ Sharing (UNOS). Recalibration and model updating were also explored.| File | Dimensione | Formato | |
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