Penile squamous cell carcinoma (pSCC) is a rare cancer with several known risk factors. High-risk HPVs are considered to be responsible for about 50% of cases1 and it is established that concomitant HIV infection accelerates disease progression.2 Although significant advancements have been made in systemic tumor therapy, the prognosis of advanced pSCC remains inauspicious with poor quality of life. We report an extraordinary response of an HIV positive patient with advanced penile SCC, treated with cemiplimab
Metastatic penile squamous cell carcinoma successfully treated with cemiplimab in an HIV patient / Proietti, I.; Skroza, N.; Filippi, L.; Balduzzi, V.; Michelini, S.; Bagni, O.; Bernardini, N.; Maddalena, P.; Mambrin, A.; Marchesiello, A.; Tolino, E.; Volpe, S.; Lichtner, M.; Porta, N.; Petrozza, V.; Potenza, C.. - In: DERMATOLOGIC THERAPY. - ISSN 1396-0296. - 34:2(2021). [10.1111/dth.14744]
Metastatic penile squamous cell carcinoma successfully treated with cemiplimab in an HIV patient
Proietti I.;Skroza N.;Balduzzi V.;Michelini S.;Bernardini N.;Maddalena P.;Mambrin A.;Marchesiello A.;Tolino E.;Volpe S.;Lichtner M.;Porta N.;Petrozza V.;Potenza C.
Conceptualization
2021
Abstract
Penile squamous cell carcinoma (pSCC) is a rare cancer with several known risk factors. High-risk HPVs are considered to be responsible for about 50% of cases1 and it is established that concomitant HIV infection accelerates disease progression.2 Although significant advancements have been made in systemic tumor therapy, the prognosis of advanced pSCC remains inauspicious with poor quality of life. We report an extraordinary response of an HIV positive patient with advanced penile SCC, treated with cemiplimab| File | Dimensione | Formato | |
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Proietti_Metastatic-penile_2021e.pdf
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Note: https://onlinelibrary.wiley.com/doi/epdf/10.1111/dth.14744
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