In both animal and plants, establishment of body axes is fundamental for proper organ development. Plant roots show two main developmental axes: the proximo-distal axis, which spans from the hypocotyl-root junction to the root tip, and the radial axis, which traverses from the vascular tissue to the epidermis.Root axes are determined in the root meristem. The root meristem occupies the tip of the root and contains self-renewing stem cells, which continuously produce new root cells. An intricate network of signalling pathways regulates meristem function and patterning to ensure proper root development and growth. In the last decade, microRNAs (miRNAs), 20-21 nucleotide-long molecules with morphogenetic activity, emerged as central regulators of root cell patterning. Their activity intersects with master regulators of meristematic activity, including phytohormones. In this review we discuss the latest findings about miRNAs activity and their interaction with other molecular networks in the formation of root meristem axes. Furthermore, we describe how these small molecules allow root growth to adapt to changes in the environment, while maintaining a correct patterning.

A small cog in a large wheel: crucial role of miRNAs in root apical meristem patterning / Bertolotti, G; Scintu, D; Dello Ioio, R. - In: JOURNAL OF EXPERIMENTAL BOTANY. - ISSN 0022-0957. - (2021). [10.1093/jxb/erab332]

A small cog in a large wheel: crucial role of miRNAs in root apical meristem patterning

Bertolotti, G
Writing – Original Draft Preparation
;
Scintu, D
Writing – Review & Editing
;
Dello Ioio, R
Writing – Original Draft Preparation
2021

Abstract

In both animal and plants, establishment of body axes is fundamental for proper organ development. Plant roots show two main developmental axes: the proximo-distal axis, which spans from the hypocotyl-root junction to the root tip, and the radial axis, which traverses from the vascular tissue to the epidermis.Root axes are determined in the root meristem. The root meristem occupies the tip of the root and contains self-renewing stem cells, which continuously produce new root cells. An intricate network of signalling pathways regulates meristem function and patterning to ensure proper root development and growth. In the last decade, microRNAs (miRNAs), 20-21 nucleotide-long molecules with morphogenetic activity, emerged as central regulators of root cell patterning. Their activity intersects with master regulators of meristematic activity, including phytohormones. In this review we discuss the latest findings about miRNAs activity and their interaction with other molecular networks in the formation of root meristem axes. Furthermore, we describe how these small molecules allow root growth to adapt to changes in the environment, while maintaining a correct patterning.
2021
Arabidopsis; longitudinal patterning; micrornas; proximo-distal patterning; root development; stem celll
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
A small cog in a large wheel: crucial role of miRNAs in root apical meristem patterning / Bertolotti, G; Scintu, D; Dello Ioio, R. - In: JOURNAL OF EXPERIMENTAL BOTANY. - ISSN 0022-0957. - (2021). [10.1093/jxb/erab332]
File allegati a questo prodotto
File Dimensione Formato  
Bertolotti_Small_2021.pdf

solo gestori archivio

Tipologia: Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 23.32 MB
Formato Adobe PDF
23.32 MB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1567287
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 6
social impact