Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disorder that causes a decline of cognitive functions and a deterioration of behavioral and social performance. According to current estimations, AD is considered the prevalent cause of dementia, accounting for 60% and 80% of cases every year. The etiology of the disease is related to both genetic and environmental factors, making AD a multifactorial disorder, with a major classification as late-onset AD and early-onset AD.

Stem cell-based 3D brain organoids for mimicking, investigating, and challenging Alzheimer's diseases / Cordella, F.; Brighi, C.; Soloperto, A.; Di Angelantonio, S.. - In: NEURAL REGENERATION RESEARCH. - ISSN 1673-5374. - 17:2(2022), pp. 330-332. [10.4103/1673-5374.317976]

Stem cell-based 3D brain organoids for mimicking, investigating, and challenging Alzheimer's diseases

Cordella F.
Membro del Collaboration Group
;
Brighi C.;Di Angelantonio S.
2022

Abstract

Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disorder that causes a decline of cognitive functions and a deterioration of behavioral and social performance. According to current estimations, AD is considered the prevalent cause of dementia, accounting for 60% and 80% of cases every year. The etiology of the disease is related to both genetic and environmental factors, making AD a multifactorial disorder, with a major classification as late-onset AD and early-onset AD.
2022
3D cell biology; Alzheimer’s disease; neurodegeneration; brain organoid; in vitro disease modeling; induced pluripotent stem cell; retinal organoid.
01 Pubblicazione su rivista::01f Lettera, Nota
Stem cell-based 3D brain organoids for mimicking, investigating, and challenging Alzheimer's diseases / Cordella, F.; Brighi, C.; Soloperto, A.; Di Angelantonio, S.. - In: NEURAL REGENERATION RESEARCH. - ISSN 1673-5374. - 17:2(2022), pp. 330-332. [10.4103/1673-5374.317976]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1565955
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