Bilingualism requires control of multiple language systems, and may lead to architectural differences in language networks obtained from clinical fMRI tasks. Emerging connectivity metrics such as k-core may capture these differences, highlighting crucial network components based on resiliency. We investigated the influence of bilingualism on clinical fMRI language tasks and characterized bilingual networks using connectivity metrics to provide a patient care benchmark. Sixteen right-handed subjects (mean age 42-years; nine males) without neurological history were included: eight native English-speaking monolinguals and eight native Spanish-speaking (L1) bilinguals with acquired English (L2). All subjects underwent fMRI with gold-standard clinical language tasks. Starting from active clusters on fMRI, we inferred the persistent functional network across subjects and ran centrality measures to characterize differences. Our results demonstrated a persistent network “core” consisting of Broca’s area, the pre-supplementary motor area, and the premotor area. K-core analysis showed that Wernicke’s area was engaged by the “core” with weaker connection in L2 than L1.

Monolingual and bilingual language networks in healthy subjects using functional MRI and graph theory / Li, Q.; Pasquini, L.; Del Ferraro, G.; Gene, M.; Peck, K. K.; Makse, H. A.; Holodny, A. I.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 11:1(2021), pp. 1-14. [10.1038/s41598-021-90151-4]

Monolingual and bilingual language networks in healthy subjects using functional MRI and graph theory

Pasquini L.
Co-primo
Conceptualization
;
2021

Abstract

Bilingualism requires control of multiple language systems, and may lead to architectural differences in language networks obtained from clinical fMRI tasks. Emerging connectivity metrics such as k-core may capture these differences, highlighting crucial network components based on resiliency. We investigated the influence of bilingualism on clinical fMRI language tasks and characterized bilingual networks using connectivity metrics to provide a patient care benchmark. Sixteen right-handed subjects (mean age 42-years; nine males) without neurological history were included: eight native English-speaking monolinguals and eight native Spanish-speaking (L1) bilinguals with acquired English (L2). All subjects underwent fMRI with gold-standard clinical language tasks. Starting from active clusters on fMRI, we inferred the persistent functional network across subjects and ran centrality measures to characterize differences. Our results demonstrated a persistent network “core” consisting of Broca’s area, the pre-supplementary motor area, and the premotor area. K-core analysis showed that Wernicke’s area was engaged by the “core” with weaker connection in L2 than L1.
2021
bilingualism; language; fmri; graph theory
01 Pubblicazione su rivista::01a Articolo in rivista
Monolingual and bilingual language networks in healthy subjects using functional MRI and graph theory / Li, Q.; Pasquini, L.; Del Ferraro, G.; Gene, M.; Peck, K. K.; Makse, H. A.; Holodny, A. I.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 11:1(2021), pp. 1-14. [10.1038/s41598-021-90151-4]
File allegati a questo prodotto
File Dimensione Formato  
Li_Monolingual-and-bilingual-language_2021.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 22.74 MB
Formato Adobe PDF
22.74 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1563495
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 5
social impact