BACKGROUND: The published colorectal cancer (CRC) outcomes after bariatric surgery (BS) are conflicting, with some anecdotal studies reporting increased risks. The present nationwide survey CRIC-ABS 2020 (Colo-Rectal Cancer Incidence-After Bariatric Surgery-2020), endorsed by the Italian Society of Obesity Surgery (SICOB), aims to report its incidence in Italy after BS, comparing the two commonest laparoscopic procedures—Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (GBP). METHODS: Two online questionnaires—first having 11 questions on SG/GBP frequency with a follow-up of 5–10 years, and the second containing 15 questions on CRC incidence and management, were administered to 53 referral bariatric, high volume centers. A standardized incidence ratio (SIR—a ratio of the observed number of cases to the expected number) with 95% confidence intervals (CI) was calculated along with CRC incidence risk computation for baseline characteristics. RESULTS: Data for 20,571 patients from 34 (63%) centers between 2010 and 2015 were collected, of which 14,431 had SG (70%) and 6140 GBP (30%). 22 patients (0.10%, mean age = 53 ± 12 years, 13 males), SG: 12 and GBP: 10, developed CRC after 4.3 ± 2.3 years. Overall incidence was higher among males for both groups (SG: 0.15% vs 0.05%; GBP: 0.35% vs 0.09%) and the GBP cohort having slightly older patients. The right colon was most affected (n = 13) and SIR categorized/sex had fewer values < 1, except for GBP males (SIR = 1.07). CONCLUSION: Low CRC incidence after BS at 10 years (0.10%), and no difference between procedures was seen, suggesting that BS does not trigger the neoplasm development.

Colorectal cancer after bariatric surgery (Cric-Abs 2020). Sicob (Italian society of obesity surgery) endorsed national survey / Ciccioriccio, M. C.; Iossa, A.; Boru, EUGENIU CRISTIAN; De Angelis, F.; Termine, P.; Giuffrè, M.; Silecchia, G.; Luigi, Angrisani; Balani, Alessandro; Bellini, Fabrizio; Borrelli, Vincenzo; Boni, Marcello; Campanile Fabio Cesare, ; Cesana, Giovanni; Ciampaglia, Franco; DE LUCA, Maurizio; De Paoli Marco Antonio, ; Foletto, Mirto; Foschi, Diego; Gentileschi, Paolo; Giardiello, Cristiano; Giovanelli, Alessandro; Godina, Mario; Lattuada, Ezio; Lucchese, Marcello; Manno, Emilio; Marinari Giuseppe Maria, ; Martines, Gennaro; Marzano, Bernardo; Millo, Paolo; Moroni, Roberto; Musella, Mario; Navarra, Giuseppe; Olmi, Stefano; Pellicanò, Natale; Peri, Andrea; Perrotta, Nicola; Pilone, Vincenzo; Piazza, Luigi; Raffaelli, Marco; Sarro, Giuliano; Schettino Angelo Michele, ; Socci, Carlo; Vuolo, Giuseppe; Zappa Marco Antonio,. - In: INTERNATIONAL JOURNAL OF OBESITY. - ISSN 1476-5497. - (2021), pp. 1-5. [10.1038/s41366-021-00910-6]

Colorectal cancer after bariatric surgery (Cric-Abs 2020). Sicob (Italian society of obesity surgery) endorsed national survey

M. C. Ciccioriccio;A. Iossa
;
Cristian eugeniu Boru;F. De Angelis;P. Termine;M. Giuffrè;G. Silecchia
Ultimo
;
Borrelli Vincenzo;De Luca Maurizio;Moroni Roberto;Perrotta Nicola;
2021

Abstract

BACKGROUND: The published colorectal cancer (CRC) outcomes after bariatric surgery (BS) are conflicting, with some anecdotal studies reporting increased risks. The present nationwide survey CRIC-ABS 2020 (Colo-Rectal Cancer Incidence-After Bariatric Surgery-2020), endorsed by the Italian Society of Obesity Surgery (SICOB), aims to report its incidence in Italy after BS, comparing the two commonest laparoscopic procedures—Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (GBP). METHODS: Two online questionnaires—first having 11 questions on SG/GBP frequency with a follow-up of 5–10 years, and the second containing 15 questions on CRC incidence and management, were administered to 53 referral bariatric, high volume centers. A standardized incidence ratio (SIR—a ratio of the observed number of cases to the expected number) with 95% confidence intervals (CI) was calculated along with CRC incidence risk computation for baseline characteristics. RESULTS: Data for 20,571 patients from 34 (63%) centers between 2010 and 2015 were collected, of which 14,431 had SG (70%) and 6140 GBP (30%). 22 patients (0.10%, mean age = 53 ± 12 years, 13 males), SG: 12 and GBP: 10, developed CRC after 4.3 ± 2.3 years. Overall incidence was higher among males for both groups (SG: 0.15% vs 0.05%; GBP: 0.35% vs 0.09%) and the GBP cohort having slightly older patients. The right colon was most affected (n = 13) and SIR categorized/sex had fewer values < 1, except for GBP males (SIR = 1.07). CONCLUSION: Low CRC incidence after BS at 10 years (0.10%), and no difference between procedures was seen, suggesting that BS does not trigger the neoplasm development.
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Note: https://doi.org/10.1038/s41366-021-00910-6
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1562931
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