Vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) are potentially severe and complex disease in its management among the various allergic eye diseases. In this regard, studies clarified the etiopathogenetic mechanisms. The workup should be multidisciplinary. The treatment includes topical and systemic medications with anti-inflammatory and immunosuppressant activity. However, a definition of nationally- and internationally-shared diagnostic protocols would also be needed and validated access to therapeutic options of proven safety and efficacy to avoid the use of galenic preparations, up to now still essential in the management of moderate-severe VKC. Finally, recognizing VKC and AKC, among rare diseases, at a national and international level would be an essential step to allow the management of VKC with adequate timings and settings within the National Health System.

Vernal keratoconjunctivitis. An update / Ghiglioni, Dg; Zicari, Am; Parisi, Gf; Marchese, G; Indolfi, C; Diaferio, L; Brindisi, G; Ciprandi, G; Marseglia, Gl; Miraglia Del Giudice, M.. - In: EUROPEAN JOURNAL OF OPHTHALMOLOGY. - ISSN 1120-6721. - 31:6(2021), pp. 1-15. [10.1177/11206721211022153]

Vernal keratoconjunctivitis. An update

Zicari AM;Indolfi C;Brindisi G;Ciprandi G
;
Miraglia Del Giudice M.
2021

Abstract

Vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) are potentially severe and complex disease in its management among the various allergic eye diseases. In this regard, studies clarified the etiopathogenetic mechanisms. The workup should be multidisciplinary. The treatment includes topical and systemic medications with anti-inflammatory and immunosuppressant activity. However, a definition of nationally- and internationally-shared diagnostic protocols would also be needed and validated access to therapeutic options of proven safety and efficacy to avoid the use of galenic preparations, up to now still essential in the management of moderate-severe VKC. Finally, recognizing VKC and AKC, among rare diseases, at a national and international level would be an essential step to allow the management of VKC with adequate timings and settings within the National Health System.
2021
keywords vernal keratoconjunctivitis; atopic keratoconjunctivitis; ocular allergy; children; adolescents
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Vernal keratoconjunctivitis. An update / Ghiglioni, Dg; Zicari, Am; Parisi, Gf; Marchese, G; Indolfi, C; Diaferio, L; Brindisi, G; Ciprandi, G; Marseglia, Gl; Miraglia Del Giudice, M.. - In: EUROPEAN JOURNAL OF OPHTHALMOLOGY. - ISSN 1120-6721. - 31:6(2021), pp. 1-15. [10.1177/11206721211022153]
File allegati a questo prodotto
File Dimensione Formato  
Ghiglioni_Vernal-keratoconjunctivitis_2021.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 203.03 kB
Formato Adobe PDF
203.03 kB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1561931
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 18
  • ???jsp.display-item.citation.isi??? 16
social impact