Radiofrequency (RF) signals as a way to remotely control smart drug delivery nanocarriers represent a promising tool to overcome traditional therapeutic issues, such as overdosing therapeutic agents with a reduced efficacy and related side effects on healthy tissues, in order to obtain a targeted release near diseased cells. Aim of this work is to provide a deep investigation on the possible effect of sine wave RF signals, of 100 kHz and 10 MHz, applied to a non-uniform random distribution of 142 liposomes, as a realistic model of a biocompatible drug delivery suspension, to study electroporation mechanisms occurring during exposure.
Planning sine waves electroporation on liposomes for drug delivery application / Caramazza, Laura; De Angelis, Annalisa; Nardoni, Martina; Paolicelli, Patrizia; Petralito, Stefania; Apollonio, Francesca; Liberti, Micaela. - (2020), pp. 1-4. (Intervento presentato al convegno 2020 IEEE MTT-S International Microwave Biomedical Conference, IMBioC 2020 tenutosi a Toulouse; France) [10.1109/IMBIoC47321.2020.9384905].
Planning sine waves electroporation on liposomes for drug delivery application
Caramazza LauraPrimo
;Paolicelli Patrizia;Petralito Stefania;Apollonio Francesca;Liberti Micaela
2020
Abstract
Radiofrequency (RF) signals as a way to remotely control smart drug delivery nanocarriers represent a promising tool to overcome traditional therapeutic issues, such as overdosing therapeutic agents with a reduced efficacy and related side effects on healthy tissues, in order to obtain a targeted release near diseased cells. Aim of this work is to provide a deep investigation on the possible effect of sine wave RF signals, of 100 kHz and 10 MHz, applied to a non-uniform random distribution of 142 liposomes, as a realistic model of a biocompatible drug delivery suspension, to study electroporation mechanisms occurring during exposure.File | Dimensione | Formato | |
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