Electroporation has become a powerful technological platform for the electromanipulation of cells and tissues for various medical and biotechnological applications. Recently, nanoporation based on nanosecond pulsed electric fields (nsPEFs) has gained great attention due to its potential to permeabilize the membrane of small vesicles. Here, the authors propose and characterize, both experimentally and through multiphysics modeling, a grounded coplanar waveguide compliant with the wideband requirements for nanosecond pulses to be used for experiments of drug delivery with liposomes activated by nsPEFs.

Experimental and numerical characterization of a grounded coplanar waveguide for nanoelectroporation applied to liposomes / Caramazza, Laura; Paffi, Alessandra; Liberti, Micaela; Apollonio, Francesca. - In: INTERNATIONAL JOURNAL OF MICROWAVE AND WIRELESS TECHNOLOGIES. - ISSN 1759-0787. - (2021), pp. 1-10. [10.1017/S1759078721000441]

Experimental and numerical characterization of a grounded coplanar waveguide for nanoelectroporation applied to liposomes

Laura Caramazza
Primo
;
Alessandra Paffi
Secondo
;
Micaela Liberti
Penultimo
;
Francesca Apollonio
Ultimo
2021

Abstract

Electroporation has become a powerful technological platform for the electromanipulation of cells and tissues for various medical and biotechnological applications. Recently, nanoporation based on nanosecond pulsed electric fields (nsPEFs) has gained great attention due to its potential to permeabilize the membrane of small vesicles. Here, the authors propose and characterize, both experimentally and through multiphysics modeling, a grounded coplanar waveguide compliant with the wideband requirements for nanosecond pulses to be used for experiments of drug delivery with liposomes activated by nsPEFs.
2021
nanosecond pulsed electric fields; drug delivery; electromagnetic measurements; multiphysics modelling; voltage measurement; experimental design
01 Pubblicazione su rivista::01a Articolo in rivista
Experimental and numerical characterization of a grounded coplanar waveguide for nanoelectroporation applied to liposomes / Caramazza, Laura; Paffi, Alessandra; Liberti, Micaela; Apollonio, Francesca. - In: INTERNATIONAL JOURNAL OF MICROWAVE AND WIRELESS TECHNOLOGIES. - ISSN 1759-0787. - (2021), pp. 1-10. [10.1017/S1759078721000441]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1561044
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