The aims of this study were to assess the ability of 16 gait indices to identify gait instability and recurrent fallers in persons with Parkinson’s disease (pwPD), regardless of age and gait speed, and to investigate their correlation with clinical and kinematic variables. The trunk acceleration patterns were acquired during the gait of 55 pwPD and 55 age-and-speed matched healthy subjects using an inertial measurement unit. We calculated the harmonic ratios (HR), percent recurrence, and percent determinism (RQAdet), coefficient of variation, normalized jerk score, and the largest Lyapunov exponent for each participant. A value of ≤1.50 for the HR in the antero-posterior direction discriminated between pwPD at Hoehn and Yahr (HY) stage 3 and healthy subjects with a 67% probability, between pwPD at HY 3 and pwPD at lower HY stages with a 73% probability, and it characterized recurrent fallers with a 77% probability. Additionally, HR in the antero-posterior direction was correlated with pelvic obliquity and rotation. RQAdet in the antero-posterior direction discriminated between pwPD and healthy subjects with 67% probability, regardless of the HY stage, and was correlated with stride duration and cadence. Therefore, HR and RQAdet in the antero-posterior direction can both be used as age-and-speed-independent markers of gait instability.

Ability of a set of trunk inertial indexes of gait to identify gait instability and recurrent fallers in parkinson’s disease / Castiglia, S. F.; Tatarelli, A.; Trabassi, D.; De Icco, R.; Grillo, V.; Ranavolo, A.; Varrecchia, T.; Magnifica, F.; Di Lenola, D.; Coppola, G.; Ferrari, D.; Denaro, A.; Tassorelli, C.; Serrao, M.. - In: SENSORS. - ISSN 1424-8220. - 21:10(2021). [10.3390/s21103449]

Ability of a set of trunk inertial indexes of gait to identify gait instability and recurrent fallers in parkinson’s disease

Castiglia S. F.;Tatarelli A.;Trabassi D.;Ranavolo A.;Varrecchia T.;Magnifica F.;Di Lenola D.;Coppola G.;Tassorelli C.;Serrao M.
2021

Abstract

The aims of this study were to assess the ability of 16 gait indices to identify gait instability and recurrent fallers in persons with Parkinson’s disease (pwPD), regardless of age and gait speed, and to investigate their correlation with clinical and kinematic variables. The trunk acceleration patterns were acquired during the gait of 55 pwPD and 55 age-and-speed matched healthy subjects using an inertial measurement unit. We calculated the harmonic ratios (HR), percent recurrence, and percent determinism (RQAdet), coefficient of variation, normalized jerk score, and the largest Lyapunov exponent for each participant. A value of ≤1.50 for the HR in the antero-posterior direction discriminated between pwPD at Hoehn and Yahr (HY) stage 3 and healthy subjects with a 67% probability, between pwPD at HY 3 and pwPD at lower HY stages with a 73% probability, and it characterized recurrent fallers with a 77% probability. Additionally, HR in the antero-posterior direction was correlated with pelvic obliquity and rotation. RQAdet in the antero-posterior direction discriminated between pwPD and healthy subjects with 67% probability, regardless of the HY stage, and was correlated with stride duration and cadence. Therefore, HR and RQAdet in the antero-posterior direction can both be used as age-and-speed-independent markers of gait instability.
2021
accelerometry; falls; gait disorders; harmonic ratio; neurologic; Parkinson’s disease; postural balance; recurrence quantification analysis; accidental falls; gait; humans; postural balance; gait disorders, neurologic; Parkinson disease
01 Pubblicazione su rivista::01a Articolo in rivista
Ability of a set of trunk inertial indexes of gait to identify gait instability and recurrent fallers in parkinson’s disease / Castiglia, S. F.; Tatarelli, A.; Trabassi, D.; De Icco, R.; Grillo, V.; Ranavolo, A.; Varrecchia, T.; Magnifica, F.; Di Lenola, D.; Coppola, G.; Ferrari, D.; Denaro, A.; Tassorelli, C.; Serrao, M.. - In: SENSORS. - ISSN 1424-8220. - 21:10(2021). [10.3390/s21103449]
File allegati a questo prodotto
File Dimensione Formato  
Castiglia_Ability_2021.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 1.19 MB
Formato Adobe PDF
1.19 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1554298
Citazioni
  • ???jsp.display-item.citation.pmc??? 11
  • Scopus 18
  • ???jsp.display-item.citation.isi??? 16
social impact