Reactive oxygen species (ROS) comprise the superoxide anion (O2•-), hydrogen peroxide (H2O2), hydroxyl radical (•OH), and singlet oxygen (1O2). ROS can damage a variety of macromolecules, including DNA, RNA, proteins, and lipids, and compromise cell viability. To prevent or reduce ROS-induced oxidative stress, bacteria utilize different ROS defense mechanisms, of which ROS scavenging enzymes, such as superoxide dismutases, catalases, and peroxidases, are the best characterized. Recently, evidence has been accumulating that some of the terminal oxidases in bacterial respiratory chains may also play a protective role against ROS. The present review covers this role of terminal oxidases in light of recent findings.

ROS defense systems and terminal oxidases in bacteria / Borisov, Vitaliy B; Siletsky, Sergey A; Nastasi, Martina R; Forte, Elena. - In: ANTIOXIDANTS. - ISSN 2076-3921. - 10:6(2021), p. 839. [10.3390/antiox10060839]

ROS defense systems and terminal oxidases in bacteria

Nastasi, Martina R;Forte, Elena
2021

Abstract

Reactive oxygen species (ROS) comprise the superoxide anion (O2•-), hydrogen peroxide (H2O2), hydroxyl radical (•OH), and singlet oxygen (1O2). ROS can damage a variety of macromolecules, including DNA, RNA, proteins, and lipids, and compromise cell viability. To prevent or reduce ROS-induced oxidative stress, bacteria utilize different ROS defense mechanisms, of which ROS scavenging enzymes, such as superoxide dismutases, catalases, and peroxidases, are the best characterized. Recently, evidence has been accumulating that some of the terminal oxidases in bacterial respiratory chains may also play a protective role against ROS. The present review covers this role of terminal oxidases in light of recent findings.
2021
bacteria; oxidative stress; reactive oxygen species; redox enzymes; terminal oxidases
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
ROS defense systems and terminal oxidases in bacteria / Borisov, Vitaliy B; Siletsky, Sergey A; Nastasi, Martina R; Forte, Elena. - In: ANTIOXIDANTS. - ISSN 2076-3921. - 10:6(2021), p. 839. [10.3390/antiox10060839]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1550123
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