The surgical treatment of secondary hepatic metastases from colorectal carcinoma

The Surgical Treatment of Secondary Hepatic Metastases from Colorectal Carcinoma. Henri KOLANI1*; Frenki VILA2; Eriol BRAHOLLI2; Eljona XHELILI3; Bledi MASATI3; Asfloral HAXHIU3; Etmont CELIKU4Abstract Introduction:Colorectal cancer is the third most common cancer and the third leading cause of mortality among men and women in our country, and is represented by a vast number of cases diagnosed and treated in our clinic slightly second to gastric cancer. More than 50% of the patients with colorectal cancer (CRC) have or will develop metastasis, with a quarter having distant metastatic disease at the time of diagnosis, most frequently in the liver. Liver metastasis is the leading cause of cancer-related morbidity and mortality in colorectal cancer. The only potentially curative treatment for liver metastasis is liver resection, but only 15% to 20% of the patients are suitable for surgical resection. Regardless the early diagnosis and the treatment strategy the survival rarely exceeds the 3-year period. Treatment: Surgical resection remains one of the major curative treatment options available to patients with colorectal liver metastases. Surgery and chemotherapy form the backbone of the treatment in patients with colorectal liver metastases.This article provides an overview of the surgical management of colorectal liver metastases. Conclusions: According to the data from retrospective and comparative studies the surgical resection remains the best choice of treatment followed by higher rates of survivability. Our experiences with cases operated with synchronous and metachronous liver metastases secondary to colorectal cancer, shows an increase in survivability by 25 to 50%, and in the meantime, there is no positive data in the conservatory treated cases limited to chemiotherapy. Keywords: Hepatic metastases; Colorectal cancer; Surgical resection.